Literature DB >> 48673

Abnormal leucocyte composition and sodium transport in essential hypertension.

R P Edmondson, R D Thomas, P J Hilton, J Patrick, N F Jones.   

Abstract

Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive patients. These abnormalities in cell sodium transport may possibly be related to mechanisms of hypertension.

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Year:  1975        PMID: 48673     DOI: 10.1016/s0140-6736(75)91947-9

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  44 in total

Review 1.  Hypertension.

Authors:  G W Ching; D G Beevers
Journal:  Postgrad Med J       Date:  1991-03       Impact factor: 2.401

2.  Hypertension symposium: newer topics on normal and abnormal blood pressure regulatory mechanisms.

Authors:  M L Tuck; M S Golub; P Eggena; J R Sowers; M Maxwell
Journal:  West J Med       Date:  1983-08

3.  Reversible inhibition of leucocyte sodium pumps by a serum factor in essential hypertension.

Authors:  V M Oh; E A Taylor
Journal:  Br Med J (Clin Res Ed)       Date:  1986-10-25

4.  Reversible inhibition of leucocyte sodium pumps by circulating serum factor in essential hypertension.

Authors:  L Poston; P J Hilton
Journal:  Br Med J (Clin Res Ed)       Date:  1986-10-18

Review 5.  Digitalislike circulating factor in hypertension: potential messenger between salt balance and intracellular sodium.

Authors:  F J Haddy
Journal:  Cardiovasc Drugs Ther       Date:  1990-03       Impact factor: 3.727

6.  The effect of oral salbutamol on cation transport measured in vivo in healthy volunteers.

Authors:  A J Wood; C J Brearley; J K Aronson; D G Grahame-Smith
Journal:  Br J Clin Pharmacol       Date:  1990-09       Impact factor: 4.335

7.  Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure.

Authors:  A M Heagerty; J D Ollerenshaw; D I Robertson; R F Bing; J D Swales
Journal:  Br Med J (Clin Res Ed)       Date:  1986-08-02

8.  Reversal by verapamil of defect in sodium transport in leucocytes in essential hypertension.

Authors:  H H Gray; L Poston; P J Hilton; S J Smith; N D Markandu; G A MacGregor
Journal:  Br Med J (Clin Res Ed)       Date:  1984-03-03

9.  Na+/Ca2+ exchange-mediated calcium entry in human lymphocytes.

Authors:  M Balasubramanyam; C Rohowsky-Kochan; J P Reeves; J P Gardner
Journal:  J Clin Invest       Date:  1994-11       Impact factor: 14.808

10.  Noradrenaline: a circulating inhibitor of sodium transport.

Authors:  A Riozzi; A M Heagerty; R F Bing; H Thurston; J D Swales
Journal:  Br Med J (Clin Res Ed)       Date:  1984-10-20
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