Literature DB >> 485580

Myelotoxicity of D-penicillamine.

A G Kay.   

Abstract

Information has been collected on 10 patients, 9 with marrow depression and 1 in whom the diagnosis was presumed. Six of the 10 patients died. The sequentially recorded blood counts on at least 5 of the patients showed a downward trend of the white cell and platelet counts while D-penicillamine was still being administered. One patient suddenly developed leucopenia and thrombocytopenia with a streptococcal septicaemia.

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Year:  1979        PMID： 485580      PMCID： PMC1000442          DOI： 10.1136/ard.38.3.232

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  12 in total

1.  NEUTROPHILIC AGRANULOCYTOSIS DURING ADMINISTRATION OF PENICILLAMINE.

Authors:  J M CORCOS; J SOLER-BECHARA; K MAYER; R H FREYBERG; R GOLDSTEIN; I JAFFE
Journal:  JAMA       Date:  1964-07-27       Impact factor: 56.272

2.  Aplastic anaemia following penicillamine.

Authors:  E D Bird
Journal:  Postgrad Med J       Date:  1974-08       Impact factor: 2.401

3.  Fatal marrow aplasia in patient on penicillamine.

Authors:  W A McAllister; J A Vale
Journal:  Lancet       Date:  1976-09-18       Impact factor: 79.321

4.  Letter: Marrow aplasia and penicillamine.

Authors: 
Journal:  Lancet       Date:  1976-09-25       Impact factor: 79.321

5.  Fatal marrow aplasia in patient on penicillamine.

Authors:  B Bourke; R N Maini; I D Griffits; J T Scott
Journal:  Lancet       Date:  1976-09-04       Impact factor: 79.321

6.  Letter: Fatal aplastic anaemia and D-penicillamine.

Authors:  A J Richards; D S Velvin; D N Whitmore; E M Williams
Journal:  Lancet       Date:  1976-03-20       Impact factor: 79.321

7.  Letter: D-penicillamine and haemolytic anaemia.

Authors:  E E Harrison; J W Hickman
Journal:  Lancet       Date:  1976-01-03       Impact factor: 79.321

8.  Is penicillamine therapy in rheumatoid arthritis influenced by previous treatment with gold?

Authors:  M Webley; E N Coomes
Journal:  Br Med J       Date:  1978-07-08

9.  Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome.

Authors:  A S Weiss; J A Markenson; M S Weiss; W H Kammerer
Journal:  Am J Med       Date:  1978-01       Impact factor: 4.965
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  12 in total

Review 1.  Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.

Authors:  B K Park; M Pirmohamed; N R Kitteringham
Journal:  Br J Clin Pharmacol       Date:  1992-11       Impact factor: 4.335

Review 2.  What happens to patients with rheumatoid arthritis? The long-term outcome of treatment.

Authors:  T D Spector; D L Scott
Journal:  Clin Rheumatol       Date:  1988-09       Impact factor: 2.980

3.  Acquired sideroblastic anaemia associated with penicillamine therapy for rheumatoid arthritis.

Authors:  L Kandola; A J Swannell; A Hunter
Journal:  Ann Rheum Dis       Date:  1995-06       Impact factor: 19.103

4.  Therapeutic workshop on modifying the disease process in rheumatoid arthritis: immunosuppression in perspective.

Authors: 
Journal:  Ann Rheum Dis       Date:  1982       Impact factor: 19.103

Review 5.  Antirheumatic drugs: clinical pharmacology and therapeutic use.

Authors:  G L Craig; W W Buchanan
Journal:  Drugs       Date:  1980-12       Impact factor: 9.546

6.  Life threatening agranulocytosis and toxic epidermal necrolysis during low dose penicillamine therapy.

Authors:  K Ward; D G Weir
Journal:  Ir J Med Sci       Date:  1981-08       Impact factor: 1.568

Review 7.  Penicillamine in rheumatoid arthritis. A problem of toxicity.

Authors:  H G Taylor; A Samanta
Journal:  Drug Saf       Date:  1992 Jan-Feb       Impact factor: 5.606

8.  HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis.

Authors:  S R Dahlqvist; H Ström; A Bjelle; E Möller
Journal:  Clin Rheumatol       Date:  1985-03       Impact factor: 2.980

9.  Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis.

Authors:  B Fishel; M Tishler; D Caspi; M Yaron
Journal:  Ann Rheum Dis       Date:  1989-07       Impact factor: 19.103

10.  Pure red cell aplasia caused by D-penicillamine treatment of rheumatoid arthritis.

Authors:  M Tishler; Y Kahn; M Yaron
Journal:  Ann Rheum Dis       Date:  1991-04       Impact factor: 19.103
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