Literature DB >> 4851865

Enhancement of pentagastrin-induced gastric acid secretion by clonidine in the conscious dog.

B P Curwain, K Endersby.   

Abstract

The effect of intravenous clonidine on pentagastrin-induced gastric acid secretion has been studied in conscious dogs with Heidenhain pouches. Dose-dependent enhancement of secretion was found in response to clonidine (5-20 mu/kg). Clonidine (20 mug/kg) increased the maximal secretory rate to pentagastrin to a value not significantly different from the maximal response to histamine.

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Year:  1974        PMID： 4851865      PMCID： PMC1776669          DOI： 10.1111/j.1476-5381.1974.tb09621.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  10 in total

1.  Actions of clonidine and 2-(2-methyl-6-ethyl-cyclohexylamino)-2-oxazoline on postganglionic autonomic nerves.

Authors:  U Werner; K Starke; H J Schümann
Journal:  Arch Int Pharmacodyn Ther       Date:  1972-02

2.  Desmethylimipramine and the hypotensive action of clonidine in the rabbit.

Authors:  R H Briant; J L Reid
Journal:  Br J Pharmacol       Date:  1972-11       Impact factor: 8.739

3.  Effect of adrenergic drugs on histamine forming capacity of human leucocytes.

Authors:  E S Assem; J J Feigenbaum
Journal:  Br J Pharmacol       Date:  1972-11       Impact factor: 8.739

4.  The influence of 2-(2,6-dichlorphenylamino)-2-imidazoline hydrochloride (clonidine) and some related compounds on gastric secretion in the anaesthetized rat.

Authors:  A Walz; P A van Zwieten
Journal:  Eur J Pharmacol       Date:  1970       Impact factor: 4.432

5.  Drug effects on gastric secretion and stress gastric hemorrhage in the rat.

Authors:  D A Brodie; V J Lotti; B G Bauer
Journal:  Am J Dig Dis       Date:  1970-02

6.  Acid response to gastrin and related peptides.

Authors:  S Konturek; M I Grossman
Journal:  Gastroenterology       Date:  1966-05       Impact factor: 22.682

7.  [Pharmacological effects of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride, a new, antihypertensive substance].

Authors:  W Hoefke; W Kobinger
Journal:  Arzneimittelforschung       Date:  1966-08

8.  The effects of isoprenaline and noradrenaline on pentagastrin-stimulated gastric acid secretion and mucosal blood flow in the dog.

Authors:  B P Curwain; P Holton
Journal:  Br J Pharmacol       Date:  1972-10       Impact factor: 8.739

9.  The measurement of dog gastric mucosal blood flow by radioactive aniline clearance compared with amidopyrine clearance.

Authors:  B P Curwain; P Holton
Journal:  J Physiol       Date:  1973-02       Impact factor: 5.182

10.  Effects of clonidine and guanethidine on peripheral sympathetic nerve function in the pithed rat.

Authors:  J M Armstrong; A L Boura
Journal:  Br J Pharmacol       Date:  1973-04       Impact factor: 8.739
  10 in total
  3 in total

1.  The effect of clonidine on gastric acid secretion in rats and dogs.

Authors:  H M Jennewein
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000

2.  Is the gastric antisecretory property of clonidine in rats of central origin [proceedings]?

Authors:  X B Pascaud; A R Roger
Journal:  Br J Pharmacol       Date:  1976-11       Impact factor: 8.739

3.  Evidence for two opposite effects of clonidine on gastric acid secretion in the dog.

Authors:  G Soldani; M Del Tacca; C Bernardini; E Martinotti; M Impicciatore
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-09       Impact factor: 3.000
  3 in total

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