Literature DB >> 4819680

Mycoplasma contamination of cultured amniotic fluid cells: potential hazard to prenatal chromosomal diagnosis.

E L Schneider, E J Stanbridge, C J Epstein, M Golbus, G Abbo-Halbasch, G Rodgers.   

Abstract

Amniotic fluid cell cultures were screened for mycoplasma contamination. Mycoplasma RNA's were observed in more than half the cultures examined. Karyotypic analyses of these contaminated cell cultures revealed a significant increase in chromosomal aberrations. These studies emphasize the need for screening for mycoplasma in cultured amniotic cells.

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Year:  1974        PMID： 4819680     DOI： 10.1126/science.184.4135.477

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Comparison of methods for the detection of Mycoplasmal contamination of cell cultures: a review.

Authors:  E L Schneider; E J Stanbridge
Journal:  In Vitro       Date:  1975 Jan-Feb

2.  Observations of de novo clones of cytogentically aberrant cells in primary fibroblast cell strains from phenotypically normal women.

Authors:  L G Littlefield; J B Mailhes
Journal:  Am J Hum Genet       Date:  1975-03       Impact factor: 11.025

3.  Abnormal skin fibroblast cytogenetics in four dysmorphic patients with normal lymphocyte chromosomes.

Authors:  R A Pagon; J G Hall; S L Davenport; J Aase; T H Norwood; H W Hoehn
Journal:  Am J Hum Genet       Date:  1979-01       Impact factor: 11.025

Review 4.  Cytogenetic effects of mycoplasmal infection of cell cultures: a review.

Authors:  G J McGarrity; V Vanaman; J Sarama
Journal:  In Vitro       Date:  1984-01

5.  Human amniotic fluid cells grown in a hormone-supplemented medium: suitability for prenatal diagnosis.

Authors:  H C Chang; O W Jones; H Masui
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

6.  Prenatal diagnosis of genetic disorders.

Authors:  M F Niermeijer; E S Sachs; M Jahodova; C Tichelaar-Klepper; W J Kleijer; H Galjaard
Journal:  J Med Genet       Date:  1976-06       Impact factor: 6.318

7.  Detection of mycoplasma contamination in tissue cultures by fluorescence microscopy.

Authors:  M Thangavelu; H Ernø; A J Therkelsen
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132
  7 in total

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