Literature DB >> 4810267

Cholera toxin: interaction of subunits with ganglioside GM1.

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Abstract

Vibrio cholerae exotoxin is an aggregate of two different noninterconvertible subunits (molecular weights about 15,000 and about 25,000). Only the smaller subunit reacts with ganglioside G(M1), a possible biological receptor. The larger subunit, found only in active toxin molecules, can be eluted with 8 molar urea from insoluble complexes of toxin, ganglioside, and cerebroside.

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Year:  1974        PMID： 4810267     DOI： 10.1126/science.183.4125.656

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  93 in total

1.  Scanning isoelectric focusing of cholera enterotoxin in polyacrylamide gels.

Authors:  W W Yotis; N Catsimpoolas; F Montiel
Journal:  Antonie Van Leeuwenhoek       Date:  1975       Impact factor: 2.271

2.  Short communications. Subunit A from cholera toxin is an activator of adenylate cyclase in pigeon erythrocytes.

Authors:  S Van Heyningen; C A King
Journal:  Biochem J       Date:  1975-01       Impact factor: 3.857

3.  The adenylate cyclase-activating activity of cholera toxin is not associated with a nicotinamide--adenine dinucleotide glycohydrolase activity.

Authors:  R M Tait; S van Heyningen
Journal:  Biochem J       Date:  1978-09-15       Impact factor: 3.857

4.  Studies on the time course and rate-limiting steps in the activation of adenylate cyclase in rat liver by cholera toxin.

Authors:  J Fischer; T R Kohler; L G Lipson; J Flores; P A Witkum; G W Sharp
Journal:  Biochem J       Date:  1978-07-01       Impact factor: 3.857

5.  The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid-binding lectin SIGLEC7 on the cell surface.

Authors:  Noboru Hashimoto; Shizuka Ito; Akiko Tsuchida; Robiul H Bhuiyan; Tetsuya Okajima; Akihito Yamamoto; Keiko Furukawa; Yuhsuke Ohmi; Koichi Furukawa
Journal:  J Biol Chem       Date:  2019-05-28       Impact factor: 5.157

6.  Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs.

Authors:  Soo-Hyun Tark; Aditi Das; Stephen Sligar; Vinayak P Dravid
Journal:  Nanotechnology       Date:  2010-10-04       Impact factor: 3.874

7.  Multivesicular bodies as a platform for formation of the Marburg virus envelope.

Authors:  Larissa Kolesnikova; Beate Berghöfer; Sandra Bamberg; Stephan Becker
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

8.  Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.

Authors:  V Bennett; E O'Keefe; P Cuatrecasaş
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

9.  Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones.

Authors:  V Bennett; L Mong; P Cuatrecasas
Journal:  J Membr Biol       Date:  1975-11-07       Impact factor: 1.843

10.  Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness.

Authors:  J Moss; P H Fishman; V C Manganiello; M Vaughan; R O Brady
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205
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