Literature DB >> 4808973

Artifical vision for the blind: electrical stimulation of visual cortex offers hope for a functional prosthesis.

W H Dobelle, M G Mladejovsky, J P Girvin.   

Abstract

Electrical stimulation of the occipital cortex resulted in discrete photic sensations or "phosphenes" in two volunteers who had been totally blind for 7 and 28 years, respectively. Stimulation of multiple electrodes allowed one patient to recognize simple patterns, including letters. Both patients made an uneventful recovery, and the success of these experiments reinforces the hope that a functional visual prosthesis can be developed, although many problems remain to be solved.

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Year:  1974        PMID: 4808973     DOI: 10.1126/science.183.4123.440

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  62 in total

Review 1.  Retinal replacement--the development of microelectronic retinal prostheses--experience with subretinal implants and new aspects.

Authors:  Helmut G Sachs; Veit-Peter Gabel
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-08-10       Impact factor: 3.117

2.  Simulation of a phosphene-based visual field: visual acuity in a pixelized vision system.

Authors:  K Cha; K Horch; R A Normann
Journal:  Ann Biomed Eng       Date:  1992       Impact factor: 3.934

3.  New methods devised specify the size and color of the spots monkeys see when striate cortex (area V1) is electrically stimulated.

Authors:  Peter H Schiller; Warren M Slocum; Michelle C Kwak; Geoffrey L Kendall; Edward J Tehovnik
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-10       Impact factor: 11.205

4.  Task-dependent V1 responses in human retinitis pigmentosa.

Authors:  Yoichiro Masuda; Hiroshi Horiguchi; Serge O Dumoulin; Ayumu Furuta; Satoru Miyauchi; Satoshi Nakadomari; Brian A Wandell
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-05-05       Impact factor: 4.799

5.  Ethical considerations for volunteer recruitment of visual prosthesis trials.

Authors:  Yu Xia; Qiushi Ren
Journal:  Sci Eng Ethics       Date:  2012-06-23       Impact factor: 3.525

6.  Properties of electrically evoked potentials activated by optic nerve stimulation with penetrating electrodes of different modes in rabbits.

Authors:  Pengjia Cao; Jingjing Sun; Yan Yan; Yao Chen; Xinyu Chai; Xiaodong Sun; Qiushi Ren; Liming Li
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-07-31       Impact factor: 3.117

Review 7.  [Status of the subretinal implant project. An overview].

Authors:  F Gekeler; E Zrenner
Journal:  Ophthalmologe       Date:  2005-10       Impact factor: 1.059

8.  Demonstration of artificial visual percepts generated through thalamic microstimulation.

Authors:  John S Pezaris; R Clay Reid
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-23       Impact factor: 11.205

9.  Visual prosthesis.

Authors:  Peter H Schiller; Edward J Tehovnik
Journal:  Perception       Date:  2008       Impact factor: 1.490

10.  Subretinal implantation and testing of polyimide film electrodes in cats.

Authors:  Helmut G Sachs; Thomas Schanze; Marcus Wilms; Andreas Rentzos; Ursula Brunner; Florian Gekeler; Lutz Hesse
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-12-01       Impact factor: 3.117

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