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Literature DB >> 4793883

In vitro effect of virazole against influenza viruses.

Abstract

The minimal inhibitory concentrations of Virazole against 32 mean tissue culture infective doses of three type A influenza strains including type A/England/42/72 (H3N2) and a type B strain in tissue culture were 0.1 and 0.05 mug/ml, respectively. The growth inhibition pattern by various Virazole concentrations of type A virus was similar to that of the type B virus. Virazole appears to be slightly more potent against the A/England/42/72 strain than are other antiinfluenzal agents.

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Year: 1973 PMID： 4793883 PMCID： PMC444610 DOI： 10.1128/AAC.4.6.641

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

4 in total

1. Inhibition of influenza viruses in vitro and in vivo by 1-adamantanamine hydrochloride.

Authors: G C Schild; R N Sutton
Journal: Br J Exp Pathol Date: 1965-06

2. Antiviral activity of cyclooctylamine hydrochloride in cell culture and mouse systems.

Authors: W B Flagg; F J Stanfield; R F Haff; R C Stewart; R J Stedman; J Gold; R J Ferlauto
Journal: Antimicrob Agents Chemother (Bethesda) Date: 1968

3. Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide.

Authors: R W Sidwell; J H Huffman; G P Khare; L B Allen; J T Witkowski; R K Robins
Journal: Science Date: 1972-08-25 Impact factor: 47.728

4. In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.

Authors: J H Huffman; R W Sidwell; G P Khare; J T Witkowski; L B Allen; R K Robins
Journal: Antimicrob Agents Chemother Date: 1973-02 Impact factor: 5.191

4 in total

7 in total

1. Efficacy of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide against influenza virus infections in mice.

Authors: F E Durr; H F Lindh; M Forbes
Journal: Antimicrob Agents Chemother Date: 1975-05 Impact factor: 5.191

Review 2. Ribavirin: a clinical overview.

Authors: H Fernandez; G Banks; R Smith
Journal: Eur J Epidemiol Date: 1986-03 Impact factor: 8.082

3. Effects of small-particle aerosols of rimantadine and ribavirin on arterial blood pH and gas tensions and lung water content of A2 influenza-infected mice.

Authors: J B Arensman; J W Dominik; D E Hilmas
Journal: Antimicrob Agents Chemother Date: 1977-07 Impact factor: 5.191

In vitro effect of virazole against influenza viruses.

1. Inhibition of influenza viruses in vitro and in vivo by 1-adamantanamine hydrochloride.

2. Antiviral activity of cyclooctylamine hydrochloride in cell culture and mouse systems.

3. Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide.

4. In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.

1. Efficacy of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide against influenza virus infections in mice.

Review 2. Ribavirin: a clinical overview.

3. Effects of small-particle aerosols of rimantadine and ribavirin on arterial blood pH and gas tensions and lung water content of A2 influenza-infected mice.

Review 4. Ribavirin and inosiplex: a review of their present status in viral diseases.

5. Comparative activity of amantadine and ribavirin against influenza virus in vitro: possible clinical relevance.

6. Comparative inhibition of influenza and parainfluenza virus replication by ribavirin in MDCK cells.

7. Plaque inhibition assay for drug susceptibility testing of influenza viruses.