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Literature DB >> 4790608

Failure of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) to stimllate interferon.

Abstract

In cultured cells, Virazole failed to stimulate either interferon or a cellular resistance which continued in its absence. Serum from Virazole-treated mice likewise contained no demonstrable interferon.

Entities: Chemical Species

Mesh：

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Year: 1973 PMID： 4790608 PMCID： PMC444450 DOI： 10.1128/AAC.3.4.534

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

7 in total

1. INTERFERON PRODUCTION INDUCED BY STATOLON.

Authors: W J KLEINSCHMIDT; J C CLINE; E B MURPHY
Journal: Proc Natl Acad Sci U S A Date: 1964-09 Impact factor: 11.205

2. Use of disposable micro tissue culture plates for antiviral and interferon induction studies.

Authors: R W Sidwell; J H Huffman
Journal: Appl Microbiol Date: 1971-11

3. Inhibition of induction of interferon synthesis in L-cells pretreated with interferon.

Authors: J S Youngner; J V Hallum
Journal: Virology Date: 1969-03 Impact factor: 3.616

4. Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide.

Authors: R W Sidwell; J H Huffman; G P Khare; L B Allen; J T Witkowski; R K Robins
Journal: Science Date: 1972-08-25 Impact factor: 47.728

5. In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.

Authors: J H Huffman; R W Sidwell; G P Khare; J T Witkowski; L B Allen; R K Robins
Journal: Antimicrob Agents Chemother Date: 1973-02 Impact factor: 5.191

6. Effect of 1-beta-D-ribofuranosyl1-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on herpes and vaccinia keratitis and encephalitis in laboratory animals.

Authors: R W Sidwell; L B Allen; G P Khare; J H Huffman; J T Witkowski; L N Simon; R K Robins
Journal: Antimicrob Agents Chemother Date: 1973-02 Impact factor: 5.191

7. Suppression by 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) of influenza virus-induced infections in mice.

Authors: G P Khare; R W Sidwell; J T Witkowski; L N Simon; R K Robins
Journal: Antimicrob Agents Chemother Date: 1973-04 Impact factor: 5.191

7 in total

3 in total