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Literature DB >> 4788039

Blood changes in experimental arthritis in two types of genetically different rats.

V Eisen, P C Freeman, C Loveday, G B West.

Abstract

1. Rats genetically resistant to dextran and other agents producing the anaphylactoid reaction (NR rats), have a higher polymorph count than do rats which react to these agents (R rats).2. NR rats do not develop polyarthritis when a hind paw is injected intradermally with Freund's adjuvant.3. The polyarthritis produced by an intravenous injection of Mycoplasma arthritidis culture develops more slowly in NR rats than in R rats.4. It is not clear whether the higher polymorph count in NR rats is a main factor in determining their resistance to adjuvant-induced arthritis.

Entities: Chemical Disease Species

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Year: 1973 PMID： 4788039 PMCID： PMC1776605 DOI： 10.1111/j.1476-5381.1973.tb08545.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

9 in total

1. STUDIES ON ADJUVANT-INDUCED POLYARTHRITIS IN RATS. 3. THE EFFECT OF "IMMUNOSUPPRESSIVE AGENTS" ON ARTHRITIS AND TUBERCULIN HYPERSENSITIVITY.

Authors: J R WARD; R S CLOUD; E L KRAWITT; R S JONES
Journal: Arthritis Rheum Date: 1964-12

3 in total

Blood changes in experimental arthritis in two types of genetically different rats.

1. STUDIES ON ADJUVANT-INDUCED POLYARTHRITIS IN RATS. 3. THE EFFECT OF "IMMUNOSUPPRESSIVE AGENTS" ON ARTHRITIS AND TUBERCULIN HYPERSENSITIVITY.

2. Proceedings: Resistance of rats to carrageenan and to adjuvant-induced arthritis.

3. Suppression of adjuvant-induced arthritis in the rat by gold sodium thiomalate.

4. Influence of gold salts on adjuvant arthritis in the rat.

5. Reactivity of wild and domesticated populations.

6. Treatment of adjuvant arthritis in rats with anti-inflammatory drugs.

7. Effects of salicylates on blood changes in mycoplasma arthritis in rats.

8. Rats resistant to the dextran anaphylactoid reaction.

9. CHEMOTHERAPY OF ARTHRITIS INDUCED IN RATS BY MYCOBACTERIAL ADJUVANT.

1. Forty years of pharmacological research.

2. Definition and classification of adverse reactions to drugs and chemicals--some genetic and environmental aspects.

3. Meloxicam: a potent inhibitor of adjuvant arthritis in the Lewis rat.