Literature DB >> 4787522

The effect of alpha-bungarotoxin on acetylcholine receptors.

B Katz, R Miledi.   

Abstract

Fluctuations of membrane potential ('membrane noise') during acetylcholineinduced depolarization have been studied by intracellular recording from endplates of frog muscle fibres. When acetylcholine sensitivity had been greatly reduced by an irreversible inhibitor (alpha-bungarotoxin), analysis of the membrane noise showed that neither the amplitude nor the time course of the 'elementary' potential change (due to the molecular depolarizing action of acetylcholine) were altered.

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Year:  1973        PMID: 4787522      PMCID: PMC1776450          DOI: 10.1111/j.1476-5381.1973.tb08278.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  7 in total

1.  ISOLATION OF NEUROTOXINS FROM THE VENOM OF BUNGARUS MULTICINCTUS AND THEIR MODES OF NEUROMUSCULAR BLOCKING ACTION.

Authors:  C C CHANG; C Y LEE
Journal:  Arch Int Pharmacodyn Ther       Date:  1963-07-01

2.  Acetylcholine receptors in muscle fibres.

Authors:  R Miledi; L T Potter
Journal:  Nature       Date:  1971-10-29       Impact factor: 49.962

3.  Further observations on acetylcholine noise.

Authors:  B Katz; R Miledi
Journal:  Nat New Biol       Date:  1971-07-28

4.  Membrane noise produced by acetylcholine.

Authors:  B Katz; R Miledi
Journal:  Nature       Date:  1970-06-06       Impact factor: 49.962

5.  The characteristics of 'end-plate noise' produced by different depolarizing drugs.

Authors:  B Katz; R Miledi
Journal:  J Physiol       Date:  1973-05       Impact factor: 5.182

6.  The binding of acetylcholine to receptors and its removal from the synaptic cleft.

Authors:  B Katz; R Miledi
Journal:  J Physiol       Date:  1973-06       Impact factor: 5.182

7.  The statistical nature of the acetycholine potential and its molecular components.

Authors:  B Katz; R Miledi
Journal:  J Physiol       Date:  1972-08       Impact factor: 5.182

  7 in total
  11 in total

1.  Drug interactions at the motor endplate.

Authors:  P R Adams
Journal:  Pflugers Arch       Date:  1975-10-28       Impact factor: 3.657

2.  Factors affecting the time course of decay of end-plate currents: a possible cooperative action of acetylcholine on receptors at the frog neuromuscular junction.

Authors:  K L Magleby; D A Terrar
Journal:  J Physiol       Date:  1975-01       Impact factor: 5.182

3.  Relaxation experiments using bath-applied suberyldicholine.

Authors:  P R Adams
Journal:  J Physiol       Date:  1977-06       Impact factor: 5.182

4.  Kinetics of unliganded acetylcholine receptor channel gating.

Authors:  M B Jackson
Journal:  Biophys J       Date:  1986-03       Impact factor: 4.033

5.  Ionic properties of the acetylcholine receptor in cultured rat myotubes.

Authors:  A K Ritchie; D M Fambrough
Journal:  J Gen Physiol       Date:  1975-06       Impact factor: 4.086

6.  Analysis of atropine action at the frog neutromuscular junction.

Authors:  A Feltz; W A Large; A Trautmann
Journal:  J Physiol       Date:  1977-07       Impact factor: 5.182

7.  Monoclonal antibodies modify acetylcholine-induced ionic channel properties in cultured chick myoballs.

Authors:  G Goldberg; D Mochly-Rosen; S Fuchs; Y Lass
Journal:  J Membr Biol       Date:  1983       Impact factor: 1.843

8.  Single cell responses of the Douglas-fir beetle,Dendroctonus pseudotsugae hopkins (Coleoptera: Scolytidae), to pheromones and host odors.

Authors:  J C Dickens; T L Payne; L C Ryker; J A Rudinsky
Journal:  J Chem Ecol       Date:  1984-04       Impact factor: 2.626

9.  The effect of procaine on the action of acetylcholine at the neuromuscular junction.

Authors:  B Katz; R Miledi
Journal:  J Physiol       Date:  1975-07       Impact factor: 5.182

10.  Mechanisms of the inhibition of endplate acetylcholine receptors by antiseptic chlorhexidine (experiments and models).

Authors:  A R Shaihutdinova; E E Nikolsky; F Vyskocil; A I Skorinkin
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2009-10-06       Impact factor: 3.000

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