Literature DB >> 475768

The kinetics of rat liver and heart mitochondrial beta-hydroxybutyrate dehydrogenase.

G A Tucker, A P Dawson.   

Abstract

The kinetic mechanisms of the beta-hydroxybutyrate dehydrogenase from rat heart and liver mitochondria were investigated. Both enzymes, show an Ordered Bi Bi mechanism and there are no major differences in the kinetic constants. In both cases, the solubilized enzyme, re-activated with phosphatidylcholine, shows kinetic properties very similar to those of the enzyme bound to the mitochondrial membrane.

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Year:  1979        PMID： 475768      PMCID： PMC1186666          DOI： 10.1042/bj1790579

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  The kinetics of enzyme-catalyzed reactions with two or more substrates or products. III. Prediction of initial velocity and inhibition patterns by inspection.

Authors:  W W CLELAND
Journal:  Biochim Biophys Acta       Date:  1963-02-12

2.  The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations.

Authors:  W W CLELAND
Journal:  Biochim Biophys Acta       Date:  1963-01-08

3.  D-beta-Hydroxybutyric dehydrogenase of muitochondria.

Authors:  A L LEHNINGER; H C SUDDUTH; J B WISE
Journal:  J Biol Chem       Date:  1960-08       Impact factor: 5.157

4.  Graphical determination of the dissociation constants for two-substrate enzyme systems.

Authors:  J R FLORINI; C S VESTLING
Journal:  Biochim Biophys Acta       Date:  1957-09

5.  Mitochondrial D- -hydroxybutyrate dehydrogenase. IV. Kinetic analysis of reaction mechanism.

Authors:  N C Nielsen; W L Zahler; S Fleischer
Journal:  J Biol Chem       Date:  1973-04-10       Impact factor: 5.157

6.  Mitochondrial D- -hydroxybutyrate dehydrogenase. 3. Isolation and characterization.

Authors:  N C Nielsen; S Fleischer
Journal:  J Biol Chem       Date:  1973-04-10       Impact factor: 5.157

7.  Beta-hydroxybutyrate dehydrogenase: lack in ruminant liver mitochondria.

Authors:  N C Nielsen; S Fleischer
Journal:  Science       Date:  1969-11-21       Impact factor: 47.728

8.  Chloride-hydroxide exchange across mitochondrial, erythrocyte and artificial lipid membranes mediated by trialkyl- and triphenyltin compounds.

Authors:  M J Selwyn; A P Dawson; M Stockdale; N Gains
Journal:  Eur J Biochem       Date:  1970-05-01

9.  D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetic mechanism from steady-state kinetics of the reaction catalysed by the enzyme in solution and covalently attached to diethylaminoethylcellulose.

Authors:  M J Preuveneers; D Peacock; E M Crook; J B Clark; K Brocklehurst
Journal:  Biochem J       Date:  1973-05       Impact factor: 3.857
  9 in total
  4 in total

1.  Metabolism of hyperpolarized 13 C-acetoacetate to β-hydroxybutyrate detects real-time mitochondrial redox state and dysfunction in heart tissue.

Authors:  Wei Chen; Gaurav Sharma; Weina Jiang; Nesmine R Maptue; Craig R Malloy; A Dean Sherry; Chalermchai Khemtong
Journal:  NMR Biomed       Date:  2019-04-10       Impact factor: 4.044

2.  Concerning the decreased D-3-hydroxybutyrate dehydrogenase activity in the liver and heart of hyperthyroid rats.

Authors:  R Lippolis; P Morini; A R Conserva; E Casalino; C Landriscina
Journal:  Mol Cell Biochem       Date:  1990-03-27       Impact factor: 3.396

3.  Decreased rate of ketone-body oxidation and decreased activity of D-3-hydroxybutyrate dehydrogenase and succinyl-CoA:3-oxo-acid CoA-transferase in heart mitochondria of diabetic rats.

Authors:  L Grinblat; L F Pacheco Bolaños; A O Stoppani
Journal:  Biochem J       Date:  1986-11-15       Impact factor: 3.857

4.  CARDIOKIN1: Computational Assessment of Myocardial Metabolic Capability in Healthy Controls and Patients With Valve Diseases.

Authors:  Titus Kuehne; Hermann-Georg Holzhütter; Nikolaus Berndt; Johannes Eckstein; Iwona Wallach; Sarah Nordmeyer; Marcus Kelm; Marieluise Kirchner; Leonid Goubergrits; Marie Schafstedde; Anja Hennemuth; Milena Kraus; Tilman Grune; Philipp Mertins
Journal:  Circulation       Date:  2021-11-11       Impact factor: 29.690
  4 in total

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