Literature DB >> 2345540

Concerning the decreased D-3-hydroxybutyrate dehydrogenase activity in the liver and heart of hyperthyroid rats.

R Lippolis1, P Morini, A R Conserva, E Casalino, C Landriscina.   

Abstract

Whereas in rat liver mitochondria the hyperthyroid state causes an increase both in fatty acid unsaturation and in the Ea of D-3-hydroxybutyrate dehydrogenase and a decrease in phase transition temperature, in hyperthyroid rat heart mitochondria these changes are negligible. D-3-hydroxybutyrate dehydrogenase in both the liver and the heart mitochondria of hyperthyroid rats is reduced by about 35% [12] but this reduction is not due to changes in membrane fluidity in either tissue. Hypothyroidism, on the other hand, affects BDH activity in neither heart nor liver.

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Year:  1990        PMID: 2345540     DOI: 10.1007/bf00226186

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN: 0300-8177            Impact factor:   3.396


  28 in total

1.  A METHOD FOR THE SIMULTANEOUS QUANTITATIVE ESTIMATION OF CYTOCHROMES A, B, C1, AND C IN MITOCHONDRIA.

Authors:  J N WILLIAMS
Journal:  Arch Biochem Biophys       Date:  1964-09       Impact factor: 4.013

Review 2.  The thyroid hormones: a thesis concerning their action.

Authors:  A J Hulbert
Journal:  J Theor Biol       Date:  1978-07-06       Impact factor: 2.691

3.  Kinetic aspects of the role of phospholipids in D-beta-hydroxybutyrate dehydrogenase activity.

Authors:  M S el Kebbaj; N Latruffe
Journal:  Arch Biochem Biophys       Date:  1986-02-01       Impact factor: 4.013

4.  Selective interaction of D-beta-hydroxybutyrate dehydrogenase with intracellular membranes.

Authors:  M Miyahara; K Utsumi; D W Deamer
Journal:  Biochim Biophys Acta       Date:  1981-02-20

5.  The kinetics of rat liver and heart mitochondrial beta-hydroxybutyrate dehydrogenase.

Authors:  G A Tucker; A P Dawson
Journal:  Biochem J       Date:  1979-06-01       Impact factor: 3.857

6.  Kinetic studies on the reactivation of D-beta-hydroxybutyrate dehydrogenase with mixtures of short-chain lecithins.

Authors:  J D Cortese; J C Vidal
Journal:  Arch Biochem Biophys       Date:  1983-07-01       Impact factor: 4.013

7.  Involvement of tyrosyl residues in the structure-function relationships of D-beta-hydroxybutyrate dehydrogenase: a phospholipid-requiring enzyme.

Authors:  M S el Kebbaj; Y Gaudemer; N Latruffe
Journal:  Arch Biochem Biophys       Date:  1986-02-01       Impact factor: 4.013

8.  Ketone-body metabolism in hyperthyroid rats: reduced activity of D-3-hydroxybutyrate dehydrogenase in both liver and heart and of succinyl-coenzyme A: 3-oxoacid coenzyme A-transferase in heart.

Authors:  R Lippolis; N Altamura; C Landriscina
Journal:  Arch Biochem Biophys       Date:  1988-01       Impact factor: 4.013

9.  Fatty-acid desaturation and microsomal lipid fatty-acid composition in experimental hyperthyroidism.

Authors:  F H Faas; W J Carter
Journal:  Biochem J       Date:  1981-03-01       Impact factor: 3.857

10.  Inactivation of D-(-)-beta-hydroxybutyrate dehydrogenase by modifiers of carboxyl and histidyl groups.

Authors:  P V Prasad; Y Hatefi
Journal:  Biochemistry       Date:  1986-05-06       Impact factor: 3.162

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