| Literature DB >> 4748511 |
J E Russell, J D Termine, L V Avioli.
Abstract
X-ray diffraction analysis of bone from chronically uremic but nonacidotic rats with normocalcemia and hyperphosphatemia revealed smaller apatite crystals and an increase in the X-ray amorphous mineral fraction when compared to age-matched, pair-fed control animals, indicating less advanced mineral maturation in the uremic animals. Studies in animals with varied degrees of chronic renal insufficiency revealed a progression of the bone crystal maturational defect with advancing uremia.Entities:
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Year: 1973 PMID: 4748511 PMCID: PMC302552 DOI: 10.1172/JCI107480
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808