Literature DB >> 1191249

The nature of the collagen cross-links in bone in the chronic uraemic state.

J E Russell, L V Avioli, G Mechanic.   

Abstract

The cross-links from NaB3H4-reduced bone collagen of chronically uraemic rats and pairfed controls were compared. The ratio of the reduced cross-links deltadelta'-dihydroxylysinonorleucine to delta-hydroxylysinonorleucine was significantly increased in the uraemic animals. The observed increment in the dihydroxylysinonorleucine:hydroxylysinonorleucine ratio was accentuated as the uraemic state advanced. The data indicate that osteodystrophy of chronic renal insufficiency is characterized by an alteration of the quantitative relations between cross-links and aldehydic precursors of bone collagen.

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Year:  1975        PMID： 1191249      PMCID： PMC1165193          DOI： 10.1042/bj1450119

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  Determination of calcium in blood serum by atomic absorption spectroscopy.

Authors:  J B WILLIS
Journal:  Nature       Date:  1960-04-16       Impact factor: 49.962

2.  Abnormal bone mineral maturation in the chronic uremic state.

Authors:  J E Russell; J D Termine; L V Avioli
Journal:  J Clin Invest       Date:  1973-11       Impact factor: 14.808

Review 3.  The cross-linking of collagen and elastin and its inhibition in osteolathyrism. Is there a relation to the aging process?

Authors:  P Bornstein
Journal:  Am J Med       Date:  1970-10       Impact factor: 4.965

4.  A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. 3. Accumulation of acid soluble collagen with a high hydroxylysine content in bone.

Authors:  K Deshmukh; M Just; M E Nimni
Journal:  Clin Orthop Relat Res       Date:  1973 Mar-Apr       Impact factor: 4.176

5.  Effect of experimental chronic renal insufficiency on bone mineral and collagen maturation.

Authors:  J E Russell; L V Avioli
Journal:  J Clin Invest       Date:  1972-12       Impact factor: 14.808

6.  Quantitative changes of bone collagen crosslinks and precursors in vitamin D deficiency.

Authors:  G L Mechanic; S U Toverud; W K Ramp
Journal:  Biochem Biophys Res Commun       Date:  1972-05-26       Impact factor: 3.575

7.  The nature of crosslinking in collagens from mineralized tissues.

Authors:  G Mechanic; P M Gallop; M L Tanzer
Journal:  Biochem Biophys Res Commun       Date:  1971-11-05       Impact factor: 3.575

8.  The intermolecular cross-link precursors in collagens as related to function. Identification of -hydroxy -amino adipic semialdehyde in tendon collagen.

Authors:  G L Mechanic
Journal:  Isr J Med Sci       Date:  1971-03

9.  Biochemistry of collagen crosslinking. Isolation of a new crosslink, hydroxylysinohydroxynorleucine, and its reduced precursor, dihydroxynorleucine, from bovine tendon.

Authors:  G Mechanic; M L Tanzer
Journal:  Biochem Biophys Res Commun       Date:  1970-12-24       Impact factor: 3.575
  9 in total
  3 in total

1.  Nonmineralized and mineralized bone collagen in bone of immobilized monkeys.

Authors:  G L Mechanic; D R Young; A J Banes; M Yamauchi
Journal:  Calcif Tissue Int       Date:  1986-08       Impact factor: 4.333

2.  Experimental renal osteodystrophy. The response to 25-hydroxycholecalciferol and dicholomethylene diphosphate therapy.

Authors:  J E Russell; J D Termine; L V Avioli
Journal:  J Clin Invest       Date:  1975-09       Impact factor: 14.808

3.  Effect of vitamin D deficiency on bone formation in the chick.

Authors:  I R Dickson; E Kodicek
Journal:  Biochem J       Date:  1979-08-15       Impact factor: 3.857
  3 in total

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