Literature DB >> 472761

Imbalance in X-chromosome expression: evidence for a human X-linked gene affecting growth of hemopoietic cells.

L Luzzatto, E A Usanga, U Bienzle, G F Esan, F A Fusuan.   

Abstract

In each of six family members who were heterozygous at the X-linked locus for glucose-6-phosphate dehydrogenase, only one or the other of the two alleles at that locus was almost exclusively expressed. The data are consistent with evidence that X-chromosome inactivation is a random process that may be followed by selection for one of the two resulting cell types on the basis of an unknown gene, which is located on the X chromosome and which can affect the rate of proliferation of hemopoietic cells in humans.

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Year:  1979        PMID： 472761     DOI： 10.1126/science.472761

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Evidence that mutations in the X-linked DDP gene cause incompletely penetrant and variable skewed X inactivation.

Authors:  R M Plenge; L Tranebjaerg; P K Jensen; C Schwartz; H F Willard
Journal:  Am J Hum Genet       Date:  1999-03       Impact factor: 11.025

Review 2.  X-linked clonality testing: interpretation and limitations.

Authors:  George L Chen; Josef T Prchal
Journal:  Blood       Date:  2007-04-13       Impact factor: 22.113

3.  Glucose 6-phosphate dehydrogenase deficiency and incidence of hematologic malignancy.

Authors:  A M Ferraris; G Broccia; T Meloni; G Forteleoni; G F Gaetani
Journal:  Am J Hum Genet       Date:  1988-03       Impact factor: 11.025

4.  X chromosome constitution and the human female phenotype.

Authors:  E Therman; C Denniston; G E Sarto; M Ulber
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

5.  The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus.

Authors:  T W Beck; M Huleihel; M Gunnell; T I Bonner; U R Rapp
Journal:  Nucleic Acids Res       Date:  1987-01-26       Impact factor: 16.971

6.  An X chromosome gene regulates hematopoietic stem cell kinetics.

Authors:  J L Abkowitz; M Taboada; G H Shelton; S N Catlin; P Guttorp; J V Kiklevich
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-31       Impact factor: 11.205

7.  G6PD Cagliari: a new low activity glucose 6-phosphate dehydrogenase variant characterized by enhanced intracellular lability.

Authors:  A Morelli; U Benatti; L Guida; A De Flora
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

8.  Electrophoretic variants of blood proteins in Japanese. IV. Prevalence and enzymologic characteristics of glucose-6-phosphate dehydrogenase variants in Hiroshima and Nagasaki.

Authors:  T Kageoka; C Satoh; K Goriki; M Fujita; S Neriishi; K Yamamura; J Kaneko; N Masunari
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

9.  Adrenoleukodystrophy: evidence for X linkage, inactivation, and selection favoring the mutant allele in heterozygous cells.

Authors:  B R Migeon; H W Moser; A B Moser; J Axelman; D Sillence; R A Norum
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

10.  Diverse point mutations in the human glucose-6-phosphate dehydrogenase gene cause enzyme deficiency and mild or severe hemolytic anemia.

Authors:  T J Vulliamy; M D'Urso; G Battistuzzi; M Estrada; N S Foulkes; G Martini; V Calabro; V Poggi; R Giordano; M Town
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205
  10 in total

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