| Literature DB >> 4724482 |
L C Clark, F Becattini, S Kaplan, V Obrock, D Cohen, C Becker.
Abstract
Perfluorinated organic liquids are useful as high capacity oxygen and carbon dioxide solvents. After intravenous infusion most of these perfluorinated emulsions are deposited in the liver and spleen in a matter of days, where they remain for the lifetime of the animal. Hence, while they may be useful as isolated organ perfusion media their value as artificial blood is limited. A family of perfluorocarbons has now been discovered, which, although deposited in the liver after circulation in the blood, leave the liver to be excreted via the lungs and skin in a matter of days without apparent harmn to the animal.Entities:
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Year: 1973 PMID: 4724482 DOI: 10.1126/science.181.4100.680
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728