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Literature DB >> 4724190

Monoamine oxidase and aldehyde dehydrogenase activity in the striatum of rats after 6-hydroxydopamine lesion of the nigrostriatal pathway.

Abstract

Monoamine oxidase and aldehyde dehydrogenase activity were significantly reduced in the striatum of rats 8 days after lesion of the nigrostriatal nerve pathway caused by 6-hydroxydopamine. Evidence is presented for the existence of an intraneuronal 'dopamine monoamine oxidase' and intraneuronal aldehyde dehydrogenase. Dopamine concentrations were reduced to 10% of their control values.

Entities: Chemical Species

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Year: 1973 PMID： 4724190 PMCID： PMC1776111 DOI： 10.1111/j.1476-5381.1973.tb08238.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

17 in total

1. Multiple forms of rat brain mitochondrial monoamine oxidase. Subcellular localization.

Authors: M C. Kroon; H Veldstra
Journal: FEBS Lett Date: 1972-08-01 Impact factor: 4.124

Review 2. Multiple forms of monoamine oxidase: functional significance.

Authors: M Sandler; M B Youdim
Journal: Pharmacol Rev Date: 1972-06 Impact factor: 25.468

3. Disposition of newly synthesized amines in cell bodies and terminals of central catechol aminergic neurons. I. Effect of amphetamine and thiorproperazine on the metabolism of CA in the caudate nucleus, the substantia nigra and the ventromedial nucleus of the hypothalamus.

Authors: F Javoy; M Hamon; J Glowinski
Journal: Eur J Pharmacol Date: 1970-05 Impact factor: 4.432

4. Effects of drugs on human blood platelet and plasma amine oxidase activity in vitro and in vivo.

Authors: D S Robinson; W Lovenberg; H Keiser; A Sjoerdsma
Journal: Biochem Pharmacol Date: 1968-01 Impact factor: 5.858

5. Tissue and subcellular distribution of mammalian aldehyde-oxydizing capacity.

Authors: R A Deitrich
Journal: Biochem Pharmacol Date: 1966-12 Impact factor: 5.858

6. Beef adrenal medulla monoamine oxidase.

Authors: K F Tipton; M B Youdim; I P Spires
Journal: Biochem Pharmacol Date: 1972-08-15 Impact factor: 5.858

7. Studies of amines in the striatum in monkeys with nigral lesions. The disposition, biosynthesis and metabolites of [3H]dopamine and [14C]serotonin in the striatum.

Authors: M Goldstein; B Anagnoste; A F Battista; W S Owen; S Nakatani
Journal: J Neurochem Date: 1969-04 Impact factor: 5.372

8. Noradrenaline metabolizing enzymes in normal and sympathetically denervated vas deferens.

Authors: B Jarrott; L L Iversen
Journal: J Neurochem Date: 1971-01 Impact factor: 5.372

9. 6-Hydroxy-dopamine induced degeneration of central monoamine neurons.

Authors: U Ungerstedt
Journal: Eur J Pharmacol Date: 1968-12 Impact factor: 4.432

10. Effects of 6-hydroxydopamine on noradrenaline-containing neurones in the rat brain.

Authors: N J Uretsky; L L Iversen
Journal: Nature Date: 1969-02-08 Impact factor: 49.962

13 in total

1. In vitro inhibition of brain mitochondrial monoamine oxidase by 6-hydroxydopamine.

Authors: M B Youdim
Journal: Br J Pharmacol Date: 1975-07 Impact factor: 8.739

2. Increased L-DOPA-derived dopamine following selective MAO-A or -B inhibition in rat striatum depleted of dopaminergic and serotonergic innervation.

Authors: O Sader-Mazbar; Y Loboda; M J Rabey; J P M Finberg
Journal: Br J Pharmacol Date: 2013-11 Impact factor: 8.739

3. Electrical stimulation and lesions of the medial forebrain bundle of the rat: changes in voluntary ethanol consumption and brain aldehyde dehydrogenase activity.

Authors: S Amir; M H Stern
Journal: Psychopharmacology (Berl) Date: 1978-04-28 Impact factor: 4.530

4. Early effects of monoamine oxidase inhibitors on dopamine metabolism and monoamine oxidase activity in the neostriatum of the rat.

Authors: F Javoy; M B Youdim; Y Agid; J Glowinski
Journal: J Neural Transm Date: 1973 Impact factor: 3.575

Review 5. Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease.

Authors: Edna Grünblatt; Peter Riederer
Journal: J Neural Transm (Vienna) Date: 2014-10-09 Impact factor: 3.575

6. 3-Methoxytyramine and normetanephrine as indicators of dopamine and noradrenaline release in mouse brain in vivo.

Authors: W Kehr
Journal: J Neural Transm Date: 1981 Impact factor: 3.575

7. Dopamine, noradrenaline and 3,4-dihydroxyphenylacetic acid (DOPAC) levels of individual brain nuclei, effects of haloperidol and pargyline.

Authors: M I Fekete; J P Herman; B Kanyicska; M Palkovits
Journal: J Neural Transm Date: 1979 Impact factor: 3.575