Literature DB >> 4724072

Human chorionic gonadotropin: its possible role in maternal lymphocyte suppression.

E W Adcock, T Teasdale, C S August, S Cox, G Meschia, T C Ballaglia, M A Naughton.   

Abstract

Human chorionic gonadotropin completely inhibits the response of lymphocytes to phytohemagglutinin. The effect is both reversible and noncytotoxic. These observations support the theory that the fetus is accepted because human chorionic gonadotropin represents trophoblastic surface antigen and blocks the action of maternal lymphocytes.

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Year:  1973        PMID： 4724072     DOI： 10.1126/science.181.4102.845

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  36 in total

1.  Human chorionic gonadotropin. Its inhibitory effect on cell-mediated immunity in vivo and in vitro.

Authors:  T Han
Journal:  Immunology       Date:  1975-09       Impact factor: 7.397

Review 2.  Immunologic and neuroendocrine interactions in pregnancy.

Authors:  R Rani; K K Mittal
Journal:  Indian J Pediatr       Date:  1989 Mar-Apr       Impact factor: 1.967

3.  Secretion of pituitary-like peptides by the human placenta.

Authors:  L H Rees
Journal:  J Clin Pathol Suppl (Assoc Clin Pathol)       Date:  1976

4.  Mitigation of septic shock in mice and rhesus monkeys by human chorionic gonadotrophin-related oligopeptides.

Authors:  N A Khan; M P M Vierboom; C van Holten-Neelen; E Breedveld; E Zuiderwijk-Sick; A Khan; I Kondova; G Braskamp; H F J Savelkoul; W A Dik; B A 't Hart; R Benner
Journal:  Clin Exp Immunol       Date:  2010-03-16       Impact factor: 4.330

5.  Cell-mediated anti-embryo cytotoxicity in human pregnancy.

Authors:  T Timonen; E Saksela
Journal:  Clin Exp Immunol       Date:  1976-03       Impact factor: 4.330

6.  Immunologic and genetic factors influencing reproduction. A review.

Authors:  T J Gill; C F Repetti
Journal:  Am J Pathol       Date:  1979-05       Impact factor: 4.307

7.  Inhibitory effect of human chorionic gonadotrophin on lymphocyte blastogenic response to mitogen, antigen and allogeneic cells.

Authors:  T Han
Journal:  Clin Exp Immunol       Date:  1974-12       Impact factor: 4.330

8.  Suppression of mixed lymphocyte reactivity by human chorionic gonadotrophin.

Authors:  C G Beling; M E Weksler
Journal:  Clin Exp Immunol       Date:  1974-12       Impact factor: 4.330

9.  Effects of short-term administration of human chorionic gonadotropin on immune functions in cryptorchid children.

Authors:  M Maghnie; A Valtorta; A Moretta; D Larizza; M A Girani; F Severi
Journal:  Eur J Pediatr       Date:  1991-02       Impact factor: 3.183

10.  Interaction of choriocarcinoma cells and human peripheral blood lymphocytes. Resistance of cultured choriocarcinoma cells to cell-mediated cytotoxicity by mitogen-activated lymphocytes.

Authors:  C S August; S T Cox; M A Naughton
Journal:  J Clin Invest       Date:  1979-03       Impact factor: 14.808
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