Literature DB >> 472337

Regional and species differences in endogenous prostaglandin biosynthesis by brain homogenates.

M S Abdel-Halim, E Anggård.   

Abstract

Endogenously formed prostaglandins (PGs) D2, E2 and F2 alpha were determined in homogenates of brain regions from rat, guinea-pig, rabbit and cat, using gas-chromatography-mass spectrometry. The main PGs formed in the brain regions of the rat were PGD2, in the guinea-pig PGD2 and PGF2 alpha, in the rabbit PGF2 alpha and in the cat PGE2. Brain regions from the same animal species showed the same pattern of PG formation. They varied, however, in the amount of total PGs formed, the limbic system and the cerebral cortex being highest and cerebellum lowest.

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Year:  1979        PMID： 472337     DOI： 10.1016/s0090-6980(79)80009-x

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  12 in total

1.  Rapid increase of prostaglandin F2-alpha in neurons after subarachnoid hemorrhage in rats: an immunohistochemical study.

Authors:  H Ogawa; N F Kassell; T Sasaki; T Nakagomi; K Hongo; T Tsukahara
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

2.  Prostaglandin D2, a neuromodulator.

Authors:  T Shimizu; N Mizuno; T Amano; O Hayaishi
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

3.  Immunohistochemical demonstration of transient increase in prostaglandin F2-alpha after recirculation in global ischemic rat brains.

Authors:  H Ogawa; N F Kassell; T Sasaki; K Hongo; T Tsukahara; S B Hudson; G I Asban; H L Tuan
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

4.  Effects of intracerebroventricular administration of prostaglandin D2 on behaviour, blood pressure and body temperature as compared to prostaglandins E2 and F2 alpha.

Authors:  U Förstermann; R Heldt; G Hertting
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

5.  Central nervous system effects of arachidonic acid, PGE2, PGF2 alpha, PGD2 and PGI2 on gastric secretion in the rat.

Authors:  J Puurunen
Journal:  Br J Pharmacol       Date:  1983-10       Impact factor: 8.739

6.  Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide.

Authors:  R Ueno; S Narumiya; T Ogorochi; T Nakayama; Y Ishikawa; O Hayaishi
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

7.  Prostaglandin inhibition of amphetamine-induced circling in mice.

Authors:  R D Schwarz; N J Uretsky; J R Bianchine
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

8.  Decreased hypothalamic prostaglandin D2 and prostaglandin E2 contents during isoflurane anaesthesia in rats.

Authors:  T Sato; I Araki; T Kushikata; H Ohkawa; H Ishihara; A Matsuki
Journal:  Can J Anaesth       Date:  1995-11       Impact factor: 5.063

9.  Immunohistochemical demonstration of increase in prostaglandin F2-alpha after recirculation in global ischemic rat brains.

Authors:  H Ogawa; T Sasaki; N F Kassell; T Nakagomi; R M Lehman; K Hongo
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

10.  Conversion of arachidonic acid to cyclooxygenase and lipoxygenase products, and incorporation into phospholipids in the mouse neuroblastoma clone, Neuro-2A.

Authors:  D L Birkle; E F Ellis
Journal:  Neurochem Res       Date:  1983-03       Impact factor: 3.996
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