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Literature DB >> 4719210

Asymptomatic primary biliary cirrhosis.

Abstract

Four asymptomatic patients are described with raised serum alkaline phosphatase values and a positive serum mitochondrial antibody test. In all four needle liver biopsy showed destructive bile duct lesions. Lymphocyte transformation to phytohaemagglutinin was normal in three and impaired in one who also suffered from rheumatoid arthritis. Two patients showed normal skin and serological test responses to dinitrochlorobenzene and haemocyanin. These four patients are believed to be suffering from asymptomatic primary biliary cirrhosis.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1973 PMID： 4719210 PMCID： PMC1412729 DOI： 10.1136/gut.14.6.444

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

11 in total

1. SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS.

Authors: J G WALKER; D DONIACH; I M ROITT; S SHERLOCK
Journal: Lancet Date: 1965-04-17 Impact factor: 79.321

2. Primary billiary cirrhosis (chronic intrahepatic obstructive jaundice).

Authors: S SHERLOCK
Journal: Gastroenterology Date: 1959-11 Impact factor: 22.682

3. Immunosuppressive therapy. The relation between clinical response and immunologic competence.

Authors: M A Swanson; R S Schwartz
Journal: N Engl J Med Date: 1967-07-27 Impact factor: 91.245

4. Mitochondrial antibodies and subclinical liver disease.

Authors: J G Walker; D Doniach; I Doniach
Journal: Q J Med Date: 1970-01

5. Immunoglobulins in chronic liver disease.

Authors: T Feizi
Journal: Gut Date: 1968-04 Impact factor: 23.059

6. Bleeding oesophageal varices as the presenting feature in primary bilirary cirrhosis.

Authors: R Zeegen; A G Stansfeld; A M Dawson; A H Hunt
Journal: Lancet Date: 1969-07-05 Impact factor: 79.321

Review 7. A unified concept of autoimmune hepatitis.

Authors: D Doniach; J G Walker
Journal: Lancet Date: 1969-04-19 Impact factor: 79.321

8. Impaired delayed hypersensitivity in primary biliary cirrhosis.

Authors: S Sherlock; R A Fox; D G James; P J Scheuer; O Sharma
Journal: Lancet Date: 1969-05-10 Impact factor: 79.321

9. Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II).

Authors: E M McKelvey; J L Fahey
Journal: J Clin Invest Date: 1965-11 Impact factor: 14.808

10. Primary biliary cirrhosis.

Authors: P Scheuer
Journal: Proc R Soc Med Date: 1967-12

10 in total

1. Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort.

Authors: M I Prince; A Chetwynd; W L Craig; J V Metcalf; O F W James
Journal: Gut Date: 2004-06 Impact factor: 23.059

Review 2. Predicting the prognosis of primary biliary cirrhosis.

Authors: J M Neuberger
Journal: Gut Date: 1989-11 Impact factor: 23.059

Review 3. Mitochondrial antibodies (AMA).

Authors: D Doniach; G Walker
Journal: Gut Date: 1974-08 Impact factor: 23.059

Asymptomatic primary biliary cirrhosis.

1. SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS.

2. Primary billiary cirrhosis (chronic intrahepatic obstructive jaundice).

3. Immunosuppressive therapy. The relation between clinical response and immunologic competence.

4. Mitochondrial antibodies and subclinical liver disease.

5. Immunoglobulins in chronic liver disease.

6. Bleeding oesophageal varices as the presenting feature in primary bilirary cirrhosis.

Review 7. A unified concept of autoimmune hepatitis.

8. Impaired delayed hypersensitivity in primary biliary cirrhosis.

9. Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II).

10. Primary biliary cirrhosis.

1. Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort.

Review 2. Predicting the prognosis of primary biliary cirrhosis.

Review 3. Mitochondrial antibodies (AMA).

4. Editorial: Mitochondrial antibodies in collagen disorders.

5. A case of asymptomatic primary biliary cirrhosis with an initial presenting feature of localized gastric varices.

6. A clinical trial of levamisole in primary biliary cirrhosis.

Review 7. Clinical, histologic, and immunopathologic features of primary biliary cirrhosis.

8. Therapeutic quandary: asymptomatic primary biliary cirrhosis associated with polymyositis.

9. Liver schistosomiasis and primary biliary cirrhosis. A clinico-pathological study.

10. Is mitochondrial antibody diagnostic of primary biliary cirrhosis?