Literature DB >> 469887

Beta-thalassaemia: increased chromosomal anomalies in lymphocyte cultures.

G B Côté, S Papadakou-Lagoyanni.   

Abstract

Lymphocyte cultures from homozygotes for the beta-thalassaemia gene were found to contain chromosomal gaps, breaks, and rearrangements more often than those from controls. Culture time seemed to have a determinant effect on the results. The possible influence of folic acid deficiency is discussed.

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Year:  1979        PMID: 469887      PMCID: PMC1012781          DOI: 10.1136/jmg.16.1.52

Source DB:  PubMed          Journal:  J Med Genet        ISSN: 0022-2593            Impact factor:   6.318


  7 in total

1.  Observations on the ultrastructure of erythropoietic cells and reticulum cells in the bone marrow of patients with homozygous beta-thalassaemia.

Authors:  S N Wickramasinghe; V Bush
Journal:  Br J Haematol       Date:  1975-08       Impact factor: 6.998

2.  The chromosome anomalies of the megaloblastic anaemias.

Authors:  C Bottura; V Coutinho
Journal:  Blut       Date:  1968-01

3.  Chromosomal abnormalities produced by folic acid antagonists.

Authors:  T J Ryan; M M Boddington; A I Spriggs
Journal:  Br J Dermatol       Date:  1965-11       Impact factor: 9.302

4.  Chromosome studies in pernicious anaemia.

Authors:  M K Jensen; A Friis-Moller
Journal:  Acta Med Scand       Date:  1967-05

5.  Cytological demonstration of mitotic crossing-over in man.

Authors:  E Therman; E M Kuhn
Journal:  Cytogenet Cell Genet       Date:  1976

6.  Cytogenetic observations in vitamin B12 and folate deficiency.

Authors:  C W Heath
Journal:  Blood       Date:  1966-06       Impact factor: 22.113

7.  Chromosomal damage in epileptics on monotherapy with carbamazepine and diphenylhydantoin.

Authors:  J Herha; G Obe
Journal:  Hum Genet       Date:  1976-12-15       Impact factor: 4.132

  7 in total
  1 in total

1.  Increased rate of sister chromatid exchanges in beta-thalassaemia.

Authors:  G B Côté; C Sarri; S Papadakou-Lagoyanni; C Mengreli; M Karagiorga-Lagana; S Pantelakis
Journal:  Blut       Date:  1982-06
  1 in total

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