Literature DB >> 468894

Comparative studies of neoplastic response to a single dose of nitroso compounds. 6. The effect of diethylnitrosamine in Syrian golden hamsters.

Y Ii, P Pour, J Althoff.   

Abstract

The effect of a single subcutaneous injection of different DEN doses was examined in adult Syrian hamsters observed for life. The minimal effective dose (threshold dose) for neoplastic response, reflected by induction of papillary polyps in the larynx and/or trachea, was 1.03 mg DEN/kg body weight. No tumors were found which could be related to treatment in other segments of the respiratory epithelium nor in other tissues.

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Year:  1979        PMID： 468894     DOI： 10.1007/bf00405344

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  8 in total

1.  Carcinogenic response of the hamster respiratory tract to single subcutaneous administrations of diethylnitrosamine at birth.

Authors:  R Montesano; U Saffiotti
Journal:  J Natl Cancer Inst       Date:  1970-02       Impact factor: 13.506

2.  [On the different effect in lung carcinoma of diethylnitrosamine in hamsters and rats].

Authors:  W DONTENWILL; U MOHR; M ZAGEL
Journal:  Z Krebsforsch       Date:  1962

3.  [Carcinoma of the respiratory tract following treatment of the golden hamster with diethylnitrosamine].

Authors:  W DONTENWILL; U MOHR
Journal:  Z Krebsforsch       Date:  1961

4.  Experimental studies on the organotropic effect of nitrosamines in the respiratory tract.

Authors:  W Dontenwill
Journal:  Food Cosmet Toxicol       Date:  1968-12

5.  [The minimal dosis for the effect of diethylnitrosamine on the trachea of the golden hamster].

Authors:  U Mohr; O Wieser; K Pielsticker
Journal:  Naturwissenschaften       Date:  1966-05

6.  Diaplacental effect of the carcinogen diethylnitrosamine in the golden hamster.

Authors:  U Mohr; J Althoff; A Authaler
Journal:  Cancer Res       Date:  1966-11       Impact factor: 12.701

7.  Induction of tumors in the Syrian hamster with diethylnitrosamine (N-nitrosodiethylamine).

Authors:  K M HERROLD; L J DUNHAM
Journal:  Cancer Res       Date:  1963-06       Impact factor: 12.701

8.  EFFECT OF ROUTE OF ADMINISTRATION ON THE CARCINOGENIC ACTION OF DIETHYLNITROSAMINE (N-NITROSODIETHYLAMINE).

Authors:  K M HERROLD
Journal:  Br J Cancer       Date:  1964-12       Impact factor: 7.640
  8 in total
  2 in total

1.  The problem of thresholds in chemical carcinogenesis some views on theoretical and practical aspects.

Authors:  R Preussmann
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

2.  Carcinogenicity of vinylethylnitrosamine in Syrian golden hamsters.

Authors:  U Green; J Althoff
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553
  2 in total

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