Literature DB >> 468893

Promoting action of croton oil on gastrocarcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

N Matsukura, T Kawachi, T Sano, K Sasajima, T Sugimura.   

Abstract

The promoting effect of croton oil on gastrocarcinogenesis by MNNG was examined in male Wistar rats. Gastric carcinomas were found in five of 10 rats given 83 micrograms/ml MNNG for three months and then 0.02% croton oil with 0.5% Tween 60 as solvent for nine months. No gastric carcinomas were found in rats given MNNG for three months and then Tween 60 only for nine months. The incidence of gastric carcinomas in these two groups was significantly different (p less than 0.05). No tumors were found in rats given only croton oil with Tween 60.

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Year:  1979        PMID： 468893     DOI： 10.1007/bf00964588

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  7 in total

1.  Systemic promoting action of phorbol in liver and lung carcinogenesis in AKR mice.

Authors:  V Armuth; I Berenblum
Journal:  Cancer Res       Date:  1972-10       Impact factor: 12.701

2.  Enhancement of skin tumorigenesis by a single application of croton oil before or soon after initiation by urethan.

Authors:  H Hennings; D Michael; E Patterson
Journal:  Cancer Res       Date:  1973-12       Impact factor: 12.701

3.  The effect of limited administration of N-methyl-N'-nitro-N-nitrosoguanidine on the induction of stomach cancer in rats.

Authors:  S Fujimura; K Kogure; T Sugimura; S Takayama
Journal:  Cancer Res       Date:  1970-03       Impact factor: 12.701

4.  Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae.

Authors:  E Hecker
Journal:  Cancer Res       Date:  1968-11       Impact factor: 12.701

5.  Phorbol as a possible systemic promoting agent for skin carcinogenesis.

Authors:  V Armuth; I Berenblum
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1976-01-02

6.  Cocarcinogens of the diterpene ester type from Croton flavens L. and esophageal cancer in Curaçao.

Authors:  J Weber; E Hecker
Journal:  Experientia       Date:  1978-06-15

7.  The role of croton oil applications, associated with a single painting of a carcinogen, in tumour induction of the mouse's skin.

Authors:  I BERENBLUM; P SHUBIK
Journal:  Br J Cancer       Date:  1947-12       Impact factor: 7.640
  7 in total
  2 in total

1.  Antinociceptive and Smooth Muscle Relaxant Activity of Croton tiglium L Seed: An In-vitro and In-vivo Study.

Authors:  Zhen Liu; Wenyuan Gao; Jingze Zhang; Jing Hu
Journal:  Iran J Pharm Res       Date:  2012       Impact factor: 1.696

Review 2.  Carcinogenicity of by-products of disinfection in mouse and rat liver.

Authors:  S L Herren-Freund; M A Pereira
Journal:  Environ Health Perspect       Date:  1986-11       Impact factor: 9.031
  2 in total

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