| Literature DB >> 4687099 |
A C Riches, J G Sharp, D B Thomas, S V Smith.
Abstract
1. The blood volume of the mouse has been measured using (59)Fe-labelled red cells to determine the red cell volume and (131)I-labelled human serum albumin to determine the plasma volume.2. Values for the blood volume of 95.0 +/- 1.5, 96.3 +/- 2.7 and 84.7 +/- 1.2 ml./kg body wt. were found for CSI female, CBA female and CBA male mice respectively.3. A marked discrepancy was observed between the venous (cardiac) haematocrit and the whole body haematocrit.4. The blood volume of the mouse must be determined from the red cell volume and the plasma volume, measured using appropriate labels, and not from the red cell volume or the plasma volume using the venous haematocrit.Entities:
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Year: 1973 PMID: 4687099 PMCID: PMC1331297 DOI: 10.1113/jphysiol.1973.sp010086
Source DB: PubMed Journal: J Physiol ISSN: 0022-3751 Impact factor: 5.182