Literature DB >> 4683115

Synthesis and biological activity of (6aS)-10,11-dihydroxyaporphine, the optical antipode of apomorphine.

W S Saari, S W King.   

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Year:  1973        PMID: 4683115     DOI: 10.1021/jm00260a022

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  5 in total

1.  Conformations and biological properties of apomorphine and its phenanthro(10,1-b,c)azepine homologue.

Authors:  D Berney; T J Petcher; J Schmutz; H P Weber; T G White
Journal:  Experientia       Date:  1975-11-15

2.  Behavioral effects of apomorphine isomers in the rat: selective locomotor-inhibitory effects of S(+)N-n-propylnorapomorphine.

Authors:  A Campbell; R J Baldessarini; M H Teicher; J L Neumeyer
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

3.  Structure-activity relationships for apomorphine congeners. Conformational energies vs. biological activities.

Authors:  I Pettersson; T Liljefors
Journal:  J Comput Aided Mol Des       Date:  1987-07       Impact factor: 3.686

Review 4.  Pharmacological Insights into the Use of Apomorphine in Parkinson's Disease: Clinical Relevance.

Authors:  Manon Auffret; Sophie Drapier; Marc Vérin
Journal:  Clin Drug Investig       Date:  2018-04       Impact factor: 2.859

5.  S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis.

Authors:  Richard J Mead; Adrian Higginbottom; Scott P Allen; Janine Kirby; Ellen Bennett; Siân C Barber; Paul R Heath; Antonio Coluccia; Neelam Patel; Iain Gardner; Andrea Brancale; Andrew J Grierson; Pamela J Shaw
Journal:  Free Radic Biol Med       Date:  2013-04-19       Impact factor: 7.376

  5 in total

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