Literature DB >> 4677596

Silver sulfadiazine: interaction with isolated deoxyribonucleic acid.

H S Rosenkranz, S Rosenkranz.   

Abstract

Silver sulfadiazine (AgSu) was found to interact with isolated deoxyribonucleic acid (DNA) to form nondissociable complexes. These complexes differ in physical and chemical properties from those that are established when silver nitrate is added to DNA. The reaction between AgSu and DNA is visualized as occurring in two stages: (i) a weak and reversible interaction (intercalation) between DNA and the sulfadiazine moiety and (ii) a tight binding involving the silver atom. In the first stage, sodium sulfadiazine competes with AgSu for the DNA.

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Year:  1972        PMID： 4677596      PMCID： PMC444323          DOI： 10.1128/AAC.2.5.373

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  The interaction of polynucleotides with cations.

Authors:  G FELSENFELD; S HUANG
Journal:  Biochim Biophys Acta       Date:  1959-07

2.  Detection of a reactive intermediate in the reaction between DNA and hydroxyurea.

Authors:  S J Jacobs; H S Rosenkranz
Journal:  Cancer Res       Date:  1970-04       Impact factor: 12.701

3.  Nucleic acid-small molecule interactions. VII. Further characterization of deoxyribonucleic acid-diamino steroid complexes.

Authors:  H R Mahler; G Green; R Goutarel; Q Khuong-Huu
Journal:  Biochemistry       Date:  1968-04       Impact factor: 3.162

4.  Thermal stability of complexes of diaminoacridines with deoxyribonucleic acids of varying base content.

Authors:  V Kleinwächter; Z Balcarová; J Bohácek
Journal:  Biochim Biophys Acta       Date:  1969-01-21

5.  The single-stranded polyadenylic acid-poly-L-lysine complex. A conformational study and characterization.

Authors:  B Davidson; G D Fasman
Journal:  Biochemistry       Date:  1969-10       Impact factor: 3.162

6.  Silver sulfadiazine--a new topical therapy for Pseudomonas in burns. Therapy of Pseudomonas infection in burns.

Authors:  C L Fox
Journal:  Arch Surg       Date:  1968-02

7.  Control of pseudomonas infection in burns by silver sulfadiazine.

Authors:  C L Fox; B W Rappole; W Stanford
Journal:  Surg Gynecol Obstet       Date:  1969-05

8.  Clinical experience with silver sulfadiazine, a new topical agent for control of pseudomonas infections in burns.

Authors:  W Stanford; B W Rappole; C L Fox
Journal:  J Trauma       Date:  1969-05

9.  Electrooptical properties of nucleic acids and nucleoproteins. II. Study of the deoxyribonucleohistone-proflavine complexes.

Authors:  C Houssier; E Fredericq
Journal:  Biochim Biophys Acta       Date:  1966-07-13

10.  Silver sulfadiazine: effect on the growth and metabolism of bacteria.

Authors:  H S Rosenkranz; H S Carr
Journal:  Antimicrob Agents Chemother       Date:  1972-11       Impact factor: 5.191
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  17 in total

1.  Effects of microamperage, medium, and bacterial concentration on iontophoretic killing of bacteria in fluid.

Authors:  C P Davis; S Weinberg; M D Anderson; G M Rao; M M Warren
Journal:  Antimicrob Agents Chemother       Date:  1989-04       Impact factor: 5.191

2.  Cytotoxicity of silver dressings on diabetic fibroblasts.

Authors:  Shi-Bo Zou; Won-Young Yoon; Seung-Kyu Han; Seong-Ho Jeong; Zheng-Jun Cui; Woo-Kyung Kim
Journal:  Int Wound J       Date:  2012-04-26       Impact factor: 3.315

Review 3.  Two-photon polymerization of microneedles for transdermal drug delivery.

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4.  Mechanism of silver sulfadiazine action on burn wound infections.

Authors:  C L Fox; S M Modak
Journal:  Antimicrob Agents Chemother       Date:  1974-06       Impact factor: 5.191

5.  Antibacterial effects of silver electrodes with weak direct current.

Authors:  J A Spadaro; T J Berger; S D Barranco; S E Chapin; R O Becker
Journal:  Antimicrob Agents Chemother       Date:  1974-11       Impact factor: 5.191

6.  The electrified catheter. Role in sterilizing urine and decreasing bacteriuria.

Authors:  A Shafik
Journal:  World J Urol       Date:  1993       Impact factor: 4.226

7.  Structural properties, cytotoxicity, and anti-inflammatory activity of silver(I) complexes with tris(p-tolyl)phosphine and 5-chloro-2-mercaptobenzothiazole.

Authors:  L Kyros; N Kourkoumelis; M Kubicki; L Male; M B Hursthouse; I I Verginadis; E Gouma; S Karkabounas; K Charalabopoulos; S K Hadjikakou
Journal:  Bioinorg Chem Appl       Date:  2010-03-29       Impact factor: 7.778

Review 8.  Use of silver in the prevention and treatment of infections: silver review.

Authors:  Amani D Politano; Kristin T Campbell; Laura H Rosenberger; Robert G Sawyer
Journal:  Surg Infect (Larchmt)       Date:  2013-02-28       Impact factor: 2.150

9.  Properties of silver sulfadiazine-resistant Enterobacter cloacae.

Authors:  H S Rosenkranz; J E Coward; T J Wlodkowski; H S Carr
Journal:  Antimicrob Agents Chemother       Date:  1974-02       Impact factor: 5.191

10.  Silver sulfadiazine: effect on the ultrastructure of Pseudomonas aeruginosa.

Authors:  J E Coward; H S Carr; H S Rosenkranz
Journal:  Antimicrob Agents Chemother       Date:  1973-05       Impact factor: 5.191
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