Literature DB >> 467587

Pentagastrin activation of adenylate cyclase in human gastric biopsy specimens.

M Becker, H J Ruoff.   

Abstract

Adenylate cyclase activity of human fundic mucosa is log-normally distributed and equally stimulated by pentagastrin and histamine. Cimetidine inhibits the histamine, but not the pentagastrin effect, which is even intensified by H2-receptor blockade. The results indicate that pentagastrin and histamine activate adenylate cyclase via distinct receptors.

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Year:  1979        PMID： 467587     DOI： 10.1007/bf01968244

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Localization of gastrin receptors in intact isolated and separated rat fundic cells.

Authors:  A Soumarmon; A M Cheret; M J Lewin
Journal:  Gastroenterology       Date:  1977-10       Impact factor: 22.682

2.  Effects of the H2-antagonists on histamine action and interaction with gastrin in isolated parietal cells.

Authors:  A H Soll
Journal:  Gastroenterology       Date:  1978-02       Impact factor: 22.682

3.  Direct stimulatory action of pentagastrin on the adenylate cyclase of rat stomach mucosa.

Authors:  J Náfrády
Journal:  Biochem Pharmacol       Date:  1977-11-01       Impact factor: 5.858

4.  A specific gastrin receptor site in the rat stomach.

Authors:  J Brown; N D Gallagher
Journal:  Biochim Biophys Acta       Date:  1978-01-03

Review 5.  Cyclic nucleotides and their role in gastrointestinal secretion.

Authors:  D V Kimbert
Journal:  Gastroenterology       Date:  1974-11       Impact factor: 22.682

6.  Adenylate cyclase of the dog gastric mucosa: stimulation by histamine and inhibition by metiamide.

Authors:  H J Ruoff; K F Sewing
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-08       Impact factor: 3.000

7.  The actions of secretagogues on oxygen uptake by isolated mammalian parietal cells.

Authors:  A H Soll
Journal:  J Clin Invest       Date:  1978-02       Impact factor: 14.808

8.  Rat gastric mucosal cAMP and cGMP after adrenergic stimulation and blockade.

Authors:  H J Ruoff
Journal:  Eur J Pharmacol       Date:  1977-08-15       Impact factor: 4.432

Review 9.  Cyclic AMP and gastric secretion: the illusive second messenger.

Authors:  E D Jacobson; W J Thompson
Journal:  Adv Cyclic Nucleotide Res       Date:  1976

10.  A protein binding assay for adenosine 3':5'-cyclic monophosphate.

Authors:  A G Gilman
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205
  10 in total

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