Literature DB >> 4670491

Butirosin, a new aminoglycosidic antibiotic complex: isolation and characterization.

H W Dion, P W Woo, N E Willmer, D L Kern, J Onaga, S A Fusari.   

Abstract

Butirosin, a new water-soluble aminoglycosidic antibiotic complex, active against gram-positive and gram-negative bacteria, has been isolated from fermentation filtrates of Bacillus circulans by ion exchange. The complex has been resolved into isomeric A and B components, C(21)H(41)N(5)O(12), by means of Dowex 1 x 1 or Dowex 1 x 2 chromatography. Properties of the free bases and the N, N', N'', N'''-tetraacetyl derivatives of butirosin A and B are given.

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Year:  1972        PMID: 4670491      PMCID: PMC444272          DOI: 10.1128/AAC.2.2.84

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  1 in total

1.  Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice.

Authors:  C L Heifetz; M W Fisher; J A Chodubski; M O DeCarlo
Journal:  Antimicrob Agents Chemother       Date:  1972-08       Impact factor: 5.191

  1 in total
  11 in total

1.  Activity of three aminoglycosides and two penicillins against four species of gram-negative bacilli.

Authors:  R J Weinstein; L S Young; W L Hewitt
Journal:  Antimicrob Agents Chemother       Date:  1975-02       Impact factor: 5.191

Review 2.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

3.  Two enzymes which phosphorylate neomycin and kanamycin in Escherichia coli strains carrying R factors.

Authors:  M Brzezinska; J Davies
Journal:  Antimicrob Agents Chemother       Date:  1973-02       Impact factor: 5.191

4.  Whole-genome analysis of bacillus velezensis ZF2, a biocontrol agent that protects cucumis sativus against corynespora leaf spot diseases.

Authors:  Shuai Xu; Xuewen Xie; Yurong Zhao; Yanxia Shi; Ali Chai; Lei Li; Baoju Li
Journal:  3 Biotech       Date:  2020-03-30       Impact factor: 2.406

5.  Biological activities of two fungistatic antibiotics produced by Bacillus cereus UW85.

Authors:  L A Silo-Suh; B J Lethbridge; S J Raffel; H He; J Clardy; J Handelsman
Journal:  Appl Environ Microbiol       Date:  1994-06       Impact factor: 4.792

6.  Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice.

Authors:  C L Heifetz; M W Fisher; J A Chodubski; M O DeCarlo
Journal:  Antimicrob Agents Chemother       Date:  1972-08       Impact factor: 5.191

Review 7.  The many roles of glutamate in metabolism.

Authors:  Mark C Walker; Wilfred A van der Donk
Journal:  J Ind Microbiol Biotechnol       Date:  2015-09-01       Impact factor: 3.346

8.  Activity of BB-K8 (amikacin) against clinical isolates resistant to one or more aminoglycoside antibiotics.

Authors:  K E Price; T A Pursiano; M D DeFuria
Journal:  Antimicrob Agents Chemother       Date:  1974-02       Impact factor: 5.191

9.  Butirosin, a new aminoglycosidic antibiotic complex: bacterial origin and some microbiological studies.

Authors:  J D Howells; L E Anderson; G L Coffey; G D Senos; M A Underhill; D L Vogler; J Ehrlich
Journal:  Antimicrob Agents Chemother       Date:  1972-08       Impact factor: 5.191

10.  Assigning the Origin of Microbial Natural Products by Chemical Space Map and Machine Learning.

Authors:  Alice Capecchi; Jean-Louis Reymond
Journal:  Biomolecules       Date:  2020-09-28
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