Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The many roles of glutamate in metabolism.

Literature DB >> 26323613

The many roles of glutamate in metabolism.

Mark C Walker¹, Wilfred A van der Donk².

Abstract

The amino acid glutamate is a major metabolic hub in many organisms and as such is involved in diverse processes in addition to its role in protein synthesis. Nitrogen assimilation, nucleotide, amino acid, and cofactor biosynthesis, as well as secondary natural product formation all utilize glutamate in some manner. Glutamate also plays a role in the catabolism of certain amines. Understanding glutamate's role in these various processes can aid in genome mining for novel metabolic pathways or the engineering of pathways for bioremediation or chemical production of valuable compounds.

Entities: Chemical Disease Gene Species

Keywords: Lanthipeptides; Lantibiotics; Natural products; Non-ribosomal peptide synthetase; Thiopeptides

Mesh：

Substances：

Year: 2015 PMID： 26323613 PMCID： PMC4753154 DOI： 10.1007/s10295-015-1665-y

Source DB: PubMed Journal: J Ind Microbiol Biotechnol ISSN： 1367-5435 Impact factor: 3.346

85 in total

1. Codon usage tabulated from international DNA sequence databases: status for the year 2000.

Authors: Y Nakamura; T Gojobori; T Ikemura
Journal: Nucleic Acids Res Date: 2000-01-01 Impact factor: 16.971

Review 2. Regulation of secondary metabolism in streptomycetes.

Authors: Mervyn J Bibb
Journal: Curr Opin Microbiol Date: 2005-04 Impact factor: 7.934

Review 3. Evolution of catabolic pathways: Genomic insights into microbial s-triazine metabolism.

Authors: N Shapir; E F Mongodin; M J Sadowsky; S C Daugherty; K E Nelson; L P Wackett
Journal: J Bacteriol Date: 2006-11-17 Impact factor: 3.490

Review 4. (p)ppGpp: still magical?

Authors: Katarzyna Potrykus; Michael Cashel
Journal: Annu Rev Microbiol Date: 2008 Impact factor: 15.500

5. Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.

Authors: Carlos Olano; Cristina Gómez; María Pérez; Martina Palomino; Antonio Pineda-Lucena; Rodrigo J Carbajo; Alfredo F Braña; Carmen Méndez; José A Salas
Journal: Chem Biol Date: 2009-10-30

6. Identification of micromonolactam, a new polyene macrocyclic lactam from two marine Micromonospora strains using chemical and molecular methods: clarification of the biosynthetic pathway from a glutamate starter unit.

Authors: Elizabeth Julia Skellam; Allison Kathleen Stewart; Wendy Karen Strangman; Jeffrey Lawson Cameron Wright
Journal: J Antibiot (Tokyo) Date: 2013-05-15 Impact factor: 2.649

7. The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm.

Authors: W A Prinz; F Aslund; A Holmgren; J Beckwith
Journal: J Biol Chem Date: 1997-06-20 Impact factor: 5.157

8. Enzyme specificity of 2-nitrotoluene 2,3-dioxygenase from Pseudomonas sp. strain JS42 is determined by the C-terminal region of the alpha subunit of the oxygenase component.

Authors: J V Parales; R E Parales; S M Resnick; D T Gibson
Journal: J Bacteriol Date: 1998-03 Impact factor: 3.490

9. Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria.

Authors: Qi Zhang; James R Doroghazi; Xiling Zhao; Mark C Walker; Wilfred A van der Donk
Journal: Appl Environ Microbiol Date: 2015-04-17 Impact factor: 4.792

10. Identification and characterization of a tyramine-glutamate ligase (MfnD) involved in methanofuran biosynthesis.

Authors: Yu Wang; Huimin Xu; Kim C Harich; Robert H White
Journal: Biochemistry Date: 2014-09-24 Impact factor: 3.162

30 in total

1. Distinctive metabolic profiles between Cystic Fibrosis mutational subclasses and lung function.

Authors: Afshan Masood; Minnie Jacob; Xinyun Gu; Mai Abdel Jabar; Hicham Benabdelkamel; Imran Nizami; Liang Li; Majed Dasouki; Anas M Abdel Rahman
Journal: Metabolomics Date: 2021-01-04 Impact factor: 4.290

2. Highly selective and sensitive detection of glutamate by an electrochemical aptasensor.

Authors: Changtong Wu; Daria Barkova; Natalia Komarova; Andreas Offenhäusser; Mariia Andrianova; Ziheng Hu; Alexander Kuznetsov; Dirk Mayer
Journal: Anal Bioanal Chem Date: 2021-11-16 Impact factor: 4.142

3. Biostimulatory Effects of Amino Acids on Phenylalanine Ammonia Lyase, Capsaicin Synthase, and Peroxidase Activities in Capsicum baccatum L.

Authors: Tilen Zamljen; Aljaz Medic; Metka Hudina; Robert Veberic; Ana Slatnar
Journal: Biology (Basel) Date: 2022-04-27

Review 4. Müller Cell Metabolic Signatures: Evolutionary Conservation and Disruption in Disease.

Authors: Rebecca L Pfeiffer; Robert E Marc; Bryan W Jones
Journal: Trends Endocrinol Metab Date: 2020-02-24 Impact factor: 12.015

5. Does metabolomic profile differ with regard to birth weight?

Authors: Harpa Vidarsdottir; Thordur Thorkelsson; Thorhallur Ingi Halldorsson; Ragnar Bjarnason; Reynir Tomas Geirsson; Piero Rinaldo; Leifur Franzson
Journal: Pediatr Res Date: 2020-06-29 Impact factor: 3.756

6. Glial loss of the metallo β-lactamase domain containing protein, SWIP-10, induces age- and glutamate-signaling dependent, dopamine neuron degeneration.

Authors: Chelsea L Gibson; Joseph T Balbona; Ashlin Niedzwiecki; Peter Rodriguez; Ken C Q Nguyen; David H Hall; Randy D Blakely
Journal: PLoS Genet Date: 2018-03-28 Impact factor: 5.917

Review 7. Chinese Herbal Medicine Interventions in Neurological Disorder Therapeutics by Regulating Glutamate Signaling.

Authors: Yan Liu; Shan Wang; Jun Kan; Jingzhi Zhang; Lisa Zhou; Yuli Huang; Yunlong Zhang
Journal: Curr Neuropharmacol Date: 2020 Impact factor: 7.363

Review 8. Evolution of glutamatergic signaling and synapses.

Authors: Leonid L Moroz; Mikhail A Nikitin; Pavlin G Poličar; Andrea B Kohn; Daria Y Romanova
Journal: Neuropharmacology Date: 2021-07-31 Impact factor: 5.273

9. Effects of low and high levels of maternal nutrition consumed for the entirety of gestation on the development of muscle, adipose tissue, bone, and the organs of Wagyu cattle fetuses.

Authors: Yi Zhang; Kounosuke Otomaru; Kazunaga Oshima; Yuji Goto; Ichiro Oshima; Susumu Muroya; Mitsue Sano; Rena Saneshima; Yukiko Nagao; Aoi Kinoshita; Yasuko Okamura; Sanggun Roh; Akira Ohtsuka; Takafumi Gotoh
Journal: Anim Sci J Date: 2021-12 Impact factor: 1.974

10. Alpha-ketoglutarate promotes skeletal muscle hypertrophy and protein synthesis through Akt/mTOR signaling pathways.

Authors: Xingcai Cai; Canjun Zhu; Yaqiong Xu; Yuanyuan Jing; Yexian Yuan; Lina Wang; Songbo Wang; Xiaotong Zhu; Ping Gao; Yongliang Zhang; Qingyan Jiang; Gang Shu
Journal: Sci Rep Date: 2016-05-26 Impact factor: 4.379