Literature DB >> 4646298

Increased brain weight-liver weight ratio as a necropsy sign of intrauterine undernutrition.

J M Anderson.   

Abstract

Comparison of the brain weight/liver weight ratio(1) with the body weight of 95 stillborn and neonatally deceased infants of gestation 25-42 weeks shows that in appropriately grown infants the mean value ratio is 2.8 and is unchanged with increasing maturity. The normal range is 1.7-4.1. Survival time has no significant effect on the ratio as studied in this necropsy population. Dysmature infants of body weight less than 1 SD below the mean body weight for gestation are characterized by a brain: liver weight ratio of 4.5 or more. On the basis of these observations the brain: liver weight ratio may be employed as a guide to the prenatal nutrition of infants at necropsy.

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Year:  1972        PMID： 4646298      PMCID： PMC477537          DOI： 10.1136/jcp.25.10.867

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  16 in total

1.  Cellular growth during early malnutrition.

Authors:  M Winick
Journal:  Pediatrics       Date:  1971-06       Impact factor: 7.124

2.  The determination of normal ranges from routine laboratory data.

Authors:  G J Neumann
Journal:  Clin Chem       Date:  1968-10       Impact factor: 8.327

Review 3.  Foetal growth retardation.

Authors:  J S Wigglesworth
Journal:  Br Med Bull       Date:  1966-01       Impact factor: 4.291

Review 4.  Neonatal hypoglycaemia.

Authors:  H J Shelley; G A Neligan
Journal:  Br Med Bull       Date:  1966-01       Impact factor: 4.291

5.  Undernutrition and the developing brain. The relevance of animal models to the human problem.

Authors:  J Dobbing
Journal:  Am J Dis Child       Date:  1970-11

6.  Changes in brain weight, cholesterol, phospholipid, and DNA content in marasmic children.

Authors:  P Rosso; J Hormazábal; M Winick
Journal:  Am J Clin Nutr       Date:  1970-10       Impact factor: 7.045

7.  Head circumference and cellular growth of the brain in normal and marasmic children.

Authors:  M Winick; P Rosso
Journal:  J Pediatr       Date:  1969-05       Impact factor: 4.406

8.  Low content of cerebral lipids in infants suffering from malnutrition.

Authors:  M A Fishman; A L Prensky; P R Dodge
Journal:  Nature       Date:  1969-02-08       Impact factor: 49.962

9.  Very low birth-weight and subsequent head growth.

Authors:  P A Davies; J P Davis
Journal:  Lancet       Date:  1970-12-12       Impact factor: 79.321

10.  Fetal growth retardation produced by experimental placental insufficiency in the rhesus monkey. I. Body weight, organ size.

Authors:  R E Myers; D E Hill; A B Holt; R E Scott; E D Mellits; D B Cheek
Journal:  Biol Neonate       Date:  1971
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  4 in total

1.  Chromosome constitution of 500 infants dying during the perinatal period. With an appendix concerning other genetic disorders among these infants.

Authors:  G A Machin; J A Crolla
Journal:  Humangenetik       Date:  1974

2.  Systemic Maternal Human sFLT1 Overexpression Leads to an Impaired Foetal Brain Development of Growth-Restricted Foetuses upon Experimental Preeclampsia.

Authors:  Rebekka Vogtmann; Lilo Valerie Burk; Meray Serdar; Rainer Kimmig; Ivo Bendix; Alexandra Gellhaus
Journal:  Oxid Med Cell Longev       Date:  2022-06-02       Impact factor: 7.310

3.  Diagnosis of fetal growth restriction in perinatal deaths using brain to liver weight ratios.

Authors:  Alexandre S Stephens; Jason P Bentley; Lee K Taylor; Susan M Arbuckle
Journal:  Pathology       Date:  2015-01       Impact factor: 5.306

4.  The association of fetal and early childhood growth with adult mental distress: evidence from the johns hopkins collaborative perinatal study birth cohort.

Authors:  Aaron A Alford
Journal:  Front Psychiatry       Date:  2013-09-05       Impact factor: 4.157
  4 in total

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