Literature DB >> 464578

In vitro activity of mezlocillin and its related compounds against aerobic and anaerobic bacteria.

H Thadepalli, I Roy, V T Bach, D Webb.   

Abstract

A total of 900 clinical isolates of aerobic (462 isolates) and anaerobic (438 isolates) bacteria were tested against mezlocillin in comparison with other penicillins, and the aerobes were also tested against cephalothin, cefoxitin, and cefamandole. Among penicillins, mezlocillin was the most effective against Escherichia coli, Klebsiella pneumoniae, Salmonella species, Pseudomonas aeruginosa, and Bacteroides fragilis. Mezlocillin was more effective than cephalothin against Klebsiella pneumoniae.

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Year:  1979        PMID： 464578      PMCID： PMC352691          DOI： 10.1128/AAC.15.3.487

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  Mezlocillin: in vitro studies of a new broad-spectrum penicillin.

Authors:  G P Bodey; T Pan
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191

2.  Susceptibility of anaerobic bacteria to 23 antimicrobial agents.

Authors:  V L Sutter; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1976-10       Impact factor: 5.191

3.  [Azlocillin and mezlocillin: two new semisynthetic acylureido-penicillins (author's transl)].

Authors:  H Lode; U Niestrath; P Koeppe; H Langmaack
Journal:  Infection       Date:  1977       Impact factor: 3.553

4.  In vitro activity of ticarcillin against anaerobic bacteria compared with that of carbenicillin and penicillin.

Authors:  I Roy; V Bach; H Thadepalli
Journal:  Antimicrob Agents Chemother       Date:  1977-02       Impact factor: 5.191
  4 in total
  8 in total

1.  Clinical evaluation of mezlocillin.

Authors:  H Thadepalli; B Rao
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191

2.  [Antibiotic concentrations in the abdominal cavity as basis for antibacterial therapy of peritonitis: penetration of mezlocillin into the peritoneal exudate].

Authors:  D H Wittmann; J Welter; H H Schassan
Journal:  Infection       Date:  1982       Impact factor: 3.553

3.  [Systemic mezlocillin prophylaxis in elective colon surgery].

Authors:  M Wenzel; M Walden; M Heinrich; B Neuhaus
Journal:  Infection       Date:  1982       Impact factor: 3.553

4.  Effect of dose on pharmacokinetics and serum bactericidal activity of mezlocillin.

Authors:  J F Flaherty; S L Barriere; J Mordenti; J G Gambertoglio
Journal:  Antimicrob Agents Chemother       Date:  1987-06       Impact factor: 5.191

Review 5.  Penicillins. A current review of their clinical pharmacology and therapeutic use.

Authors:  Dilip Nathwani; Martin J Wood
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

6.  Comparative in vitro antibacterial activity of seven semi-synthetic penicillins against aerobic gram-negative bacteria and enterococci.

Authors:  A Thabaut; J L Durosoir; P Saliou
Journal:  Infection       Date:  1982       Impact factor: 3.553

7.  Statistical comparison of the antibacterial activities of broad-spectrum penicillins against gram-negative bacilli.

Authors:  R J Fass
Journal:  Antimicrob Agents Chemother       Date:  1983-08       Impact factor: 5.191

8.  [In vitro effect of acylureido penicillins and mezlocillin on anaerobic sporeless gram-negative rods of genus Bacteroides].

Authors:  C Höhne
Journal:  Infection       Date:  1982       Impact factor: 3.553
  8 in total

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