Literature DB >> 4635968

Potential bioreductive alkylating agents. 1. Benzoquinone derivatives.

A J Lin, L A Cosby, C W Shansky, A C Sartorelli.   

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Year:  1972        PMID： 4635968     DOI： 10.1021/jm00282a011

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  18 in total

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Review 2.  Enzymology of bioreductive drug activation.

Authors:  D Ross; H D Beall; D Siegel; R D Traver; D L Gustafson
Journal:  Br J Cancer Suppl       Date:  1996-07

3.  Six degrees of separation: the oxygen effect in the development of radiosensitizers.

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Review 4.  Targeting hypoxia in cancer therapy.

Authors:  William R Wilson; Michael P Hay
Journal:  Nat Rev Cancer       Date:  2011-06       Impact factor: 60.716

5.  DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2).

Authors:  Goutam Chowdhury; Venkatraman Junnotula; J Scott Daniels; Marc M Greenberg; Kent S Gates
Journal:  J Am Chem Soc       Date:  2007-09-27       Impact factor: 15.419

6.  Comparison of the cytotoxic effect of lapachol, alpha-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells.

Authors:  Eduardo J S Salustiano; Chaquip D Netto; Renata F Fernandes; Alcides J M da Silva; Thiago S Bacelar; Carolina P Castro; Camilla D Buarque; Raquel C Maia; Vivian M Rumjanek; Paulo R R Costa
Journal:  Invest New Drugs       Date:  2009-03-04       Impact factor: 3.850

7.  Mouse liver NAD(P)H:quinone acceptor oxidoreductase: protein sequence analysis by tandem mass spectrometry, cDNA cloning, expression in Escherichia coli, and enzyme activity analysis.

Authors:  S Chen; P E Clarke; P A Martino; P S Deng; C H Yeh; T D Lee; H J Prochaska; P Talalay
Journal:  Protein Sci       Date:  1994-08       Impact factor: 6.725

Review 8.  Hypoxia Imaging As a Guide for Hypoxia-Modulated and Hypoxia-Activated Therapy.

Authors:  Jeffrey R Brender; Yu Saida; Nallathamby Devasahayam; Murali C Krishna; Shun Kishimoto
Journal:  Antioxid Redox Signal       Date:  2022-01       Impact factor: 8.401

9.  In vitro activity of the novel indoloquinone EO-9 and the influence of pH on cytotoxicity.

Authors:  R M Phillips; P B Hulbert; M C Bibby; N R Sleigh; J A Double
Journal:  Br J Cancer       Date:  1992-03       Impact factor: 7.640

Review 10.  SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours.

Authors:  J M Brown
Journal:  Br J Cancer       Date:  1993-06       Impact factor: 7.640
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