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Literature DB >> 8763836

Enzymology of bioreductive drug activation.

D Ross¹, H D Beall, D Siegel, R D Traver, D L Gustafson.

Abstract

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Year: 1996 PMID： 8763836 PMCID： PMC2150032

Source DB: PubMed Journal: Br J Cancer Suppl ISSN： 0306-9443

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75 in total

1. On the catalytic function of heart flavoprotein.

Authors: H S Corran; D E Green; F B Straub
Journal: Biochem J Date: 1939-05 Impact factor: 3.857

2. The one-electron reduction potential of several substrates can be related to their reduction rates by cytochrome P-450 reductase.

Authors: J Butler; B M Hoey
Journal: Biochim Biophys Acta Date: 1993-01-15

3. Generation of hydroxyl radical by anticancer quinone drugs, carbazilquinone, mitomycin C, aclacinomycin A and adriamycin, in the presence of NADPH-cytochrome P-450 reductase.

Authors: T Komiyama; T Kikuchi; Y Sugiura
Journal: Biochem Pharmacol Date: 1982-11-15 Impact factor: 5.858

4. NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.

Authors: N R Bachur; S L Gordon; M V Gee; H Kon
Journal: Proc Natl Acad Sci U S A Date: 1979-02 Impact factor: 11.205

5. Bioactivation of CB 1954: reaction of the active 4-hydroxylamino derivative with thioesters to form the ultimate DNA-DNA interstrand crosslinking species.

Authors: R J Knox; F Friedlos; T Marchbank; J J Roberts
Journal: Biochem Pharmacol Date: 1991-10-09 Impact factor: 5.858

6. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.

Authors: R D Traver; T Horikoshi; K D Danenberg; T H Stadlbauer; P V Danenberg; D Ross; N W Gibson
Journal: Cancer Res Date: 1992-02-15 Impact factor: 12.701

7. pH-dependent inactivation of DT-diaphorase by mitomycin C and porfiromycin.

Authors: D Siegel; H Beall; M Kasai; H Arai; N W Gibson; D Ross
Journal: Mol Pharmacol Date: 1993-12 Impact factor: 4.436

8. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver.

Authors: H J Prochaska; P Talalay
Journal: Cancer Res Date: 1988-09-01 Impact factor: 12.701

Review 9. Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies.

Authors: D Ross; H Beall; R D Traver; D Siegel; R M Phillips; N W Gibson
Journal: Oncol Res Date: 1994 Impact factor: 5.574

10. Indoloquinone EO9: DNA interstrand cross-linking upon reduction by DT-diaphorase or xanthine oxidase.

Authors: M Maliepaard; A Wolfs; S E Groot; N J de Mol; L H Janssen
Journal: Br J Cancer Date: 1995-04 Impact factor: 7.640

14 in total

1. Luminescent Probe Based Techniques for Hypoxia Imaging.

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Journal: J Nanomed Res Date: 2017-11-20

2. Applications of azo-based probes for imaging retinal hypoxia.

Authors: Md Imam Uddin; Stephanie M Evans; Jason R Craft; Lawrence J Marnett; Md Jashim Uddin; Ashwath Jayagopal
Journal: ACS Med Chem Lett Date: 2015-02-12 Impact factor: 4.345

3. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones.

Authors: D L Gustafson; H D Beall; E M Bolton; D Ross; C A Waldren
Journal: Mol Pharmacol Date: 1996-10 Impact factor: 4.436

4. Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity.

Authors: Marie A Colucci; Philip Reigan; David Siegel; Aurélie Chilloux; David Ross; Christopher J Moody
Journal: J Med Chem Date: 2007-10-18 Impact factor: 7.446

5. Enzymatic reduction and glutathione conjugation of benzoquinone ansamycin heat shock protein 90 inhibitors: relevance for toxicity and mechanism of action.

Authors: Wenchang Guo; Philip Reigan; David Siegel; David Ross
Journal: Drug Metab Dispos Date: 2008-07-17 Impact factor: 3.922

6. Impact of tumor blood flow modulation on tumor sensitivity to the bioreductive drug banoxantrone.

Authors: Eugene Manley; David J Waxman
Journal: J Pharmacol Exp Ther Date: 2012-11-28 Impact factor: 4.030

7. The p53-dependent apoptotic pathway of breast cancer cells (BC-M1) induced by the bis-type bioreductive compound aziridinylnaphthoquinone.

Authors: Yu-Ping Yang; Hsien-Shou Kuo; Hsin-Da Tsai; Yi-Chen Peng; Yuh-Ling Lin
Journal: Breast Cancer Res Date: 2004-11-04 Impact factor: 6.466