Literature DB >> 4628095

An osmotically fragile mutant of Bacillus subtilis with an active membrane-associated phospholipase A 1 .

C Kent, W J Lennarz.   

Abstract

By use of a newly developed procedure for the isolation of mutants with osmotically fragile protoplasts, a mutant of Bacillus subtilis was isolated that has a very active enzyme system for the catabolism of phospholipids via the sequential action of a phospholipase A(1) (EC 3.1.1.4) and a lysophospholipase (EC 3.1.1.5). The wild-type bacteria contain no detectable phospholipase A(1) activity, but do contain a protein that specifically inhibits the phospholipase A(1) in the mutant. This protein may play an important role in the control of phospholipid catabolism.

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Year:  1972        PMID: 4628095      PMCID: PMC389646          DOI: 10.1073/pnas.69.10.2793

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  5 in total

1.  Sequential replication of the Bacillus subtilis chromosome. II. Isotopic transfer experiments.

Authors:  H YOSHIKAWA; N SUEOKA
Journal:  Proc Natl Acad Sci U S A       Date:  1963-06       Impact factor: 11.205

2.  Quantitative analysis of phospholipids by thin-layer chromatography.

Authors:  V P Skipski; R F Peterson; M Barclay
Journal:  Biochem J       Date:  1964-02       Impact factor: 3.857

3.  A phospholipase in Bacillus megaterium unique to spores and sporangia.

Authors:  D M Raybin; L L Bertsch; A Kornberg
Journal:  Biochemistry       Date:  1972-05-09       Impact factor: 3.162

4.  A membrane-bound phospholipase A1 purified from Escherichia coli.

Authors:  C J Scandella; A Kornberg
Journal:  Biochemistry       Date:  1971-11-23       Impact factor: 3.162

5.  Metabolism of Phosphatidylglycerol and Lysyl Phosphatidylglycerol in Staphylococcus aureus.

Authors:  R M Gould; W J Lennarz
Journal:  J Bacteriol       Date:  1970-12       Impact factor: 3.490

  5 in total
  9 in total

1.  Study of bound phospholipase activities of fungal mycelia using an organic solvent system.

Authors:  J A Blain; J D Patterson; C E Shaw; M W Akhtar
Journal:  Lipids       Date:  1976-07       Impact factor: 1.880

2.  Characterization of phospholipase A2 of mycoplasma species.

Authors:  S Bhandari; P J Asnani
Journal:  Folia Microbiol (Praha)       Date:  1989       Impact factor: 2.099

3.  Incorporation and modification of exogenous phosphatidylcholines by mycoplasmas.

Authors:  S Rottem; L Adar; Z Gross; Z Ne'eman; P J Davis
Journal:  J Bacteriol       Date:  1986-07       Impact factor: 3.490

4.  Enzymology, genetics, and regulation of membrane phospholipid synthesis in Escherichia coli.

Authors:  C R Raetz
Journal:  Microbiol Rev       Date:  1978-09

5.  Procedure for the isolation of mutants of Bacillus subtilis with defective cytoplasmic membranes.

Authors:  C Kent; S S Krag; W J Lennarz
Journal:  J Bacteriol       Date:  1973-02       Impact factor: 3.490

6.  Phospholipid composition and phospholipase A activity of Neisseria gonorrhoeae.

Authors:  L M Senff; W S Wegener; G F Brooks; W R Finnerty; R A Makula
Journal:  J Bacteriol       Date:  1976-08       Impact factor: 3.490

7.  Bacillus subtilis mutant with temperature-sensitive net synthesis of phosphatidylethanolamine.

Authors:  V Lindgren; E Holmgren; L Rutberg
Journal:  J Bacteriol       Date:  1977-11       Impact factor: 3.490

8.  Outer membrane phospholipase A from Acinetobacter sp. HO1-N.

Authors:  R E Torregrossa; R A Makula; W R Finnerty
Journal:  J Bacteriol       Date:  1977-08       Impact factor: 3.490

9.  Phospholipid metabolism in Neisseria gonorrhoeae: phospholipid hydrolysis in nongrowing cells.

Authors:  A F Cacciapuoti; W S Wegener; S A Morse
Journal:  Lipids       Date:  1979-08       Impact factor: 1.880

  9 in total

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