Literature DB >> 4610078

Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2.

A J Munro, M J Taussig, R Campbell, H Williams, Y Lawson.   

Abstract

Mouse thymus cells, educated to poly(tyrosyl,glutamyl)-polyDLalanyl--polylysyl [(T,G)-A--L], release an antigen-specific factor on brief culture in vitro. The factor cooperates with bone marrow cells in the antibody response to (T,G)-A--L in irradiated recipients. Its mol wt determined from Sephadex G100 chromatography is in the region of 50,000. The factor is removed by specific antigen-coated columns, but not by anti-immunoglobulin (anti-Fab, anti-micro, anti-Fv) adsorbents. The factor is removed by alloantisera directed against the H-2 haplotype of the strain in which it is produced. Moreover, only antisera with specificity for the K side of H-2 were successful in removing the factor activity.

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Year:  1974        PMID： 4610078      PMCID： PMC2139753          DOI： 10.1084/jem.140.6.1579

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  22 in total

1.  Studies on the chemical basis of the antigenicity of proteins. 5. Synthesis, characterization and immunogenicity of some multichain and linear polypeptides containing tyrosine.

Authors:  M SELA; S FUCHS; R ARNON
Journal:  Biochem J       Date:  1962-10       Impact factor: 3.857

2.  T cell factor which can replace T cells in vivo.

Authors:  M J Taussig
Journal:  Nature       Date:  1974-03-15       Impact factor: 49.962

3.  Antigen binding T and B lymphocytes. II. Studies on the inhibition of antigen binding to T and B cells by anti-immunoglobulin and anti-H-2 sera.

Authors:  G J Hämmerling; H O McDevitt
Journal:  J Immunol       Date:  1974-05       Impact factor: 5.422

Review 4.  The allogeneic effect on immune responses: model for regulatory influences of T lymphocytes on the immune system.

Authors:  D H Katz
Journal:  Transplant Rev       Date:  1972

5.  Role of optical configuration in the immunogenicity and specificity of synthetic antigens derived from multichain polyproline.

Authors:  J C Jaton; M Sela
Journal:  J Biol Chem       Date:  1968-11-10       Impact factor: 5.157

6.  Evidence for surface-associated immunoglobulin on T and B lymphocytes.

Authors:  U Hämmerling; K Rajewsky
Journal:  Eur J Immunol       Date:  1971-12       Impact factor: 5.532

7.  Isolation and partial characterization of lymphocyte surface immunoglobulins.

Authors:  J J Marchalonis; R E Cone; J L Atwell
Journal:  J Exp Med       Date:  1972-04-01       Impact factor: 14.307

8.  Plaque Formation in Agar by Single Antibody-Producing Cells.

Authors:  N K Jerne; A A Nordin
Journal:  Science       Date:  1963-04-26       Impact factor: 47.728

9.  Blocking and redistribution ("capping") of antigen receptors on T and B lymphocytes by anti-immunoglobulin antibody.

Authors:  G Roelants; L Forni; B Pernis
Journal:  J Exp Med       Date:  1973-04-01       Impact factor: 14.307

10.  Antigen-specific thymus cell factors in the genetic control of the immune response to poly-(tyrosyl, glutamyl)-poly-D, L-alanyl--poly-lysyl.

Authors:  J Taussig; E Mozes; R Isac
Journal:  J Exp Med       Date:  1974-08-01       Impact factor: 14.307
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  29 in total

Review 1.  Antigen specific T cell factors.

Authors:  M Feldmann; S Kontiainen
Journal:  Mol Cell Biochem       Date:  1980-05-07       Impact factor: 3.396

Review 2.  Antigen-specific T-cell factors.

Authors:  M J Taussig
Journal:  Immunology       Date:  1980-12       Impact factor: 7.397

Review 3.  Recognition of antigens by T lymphocytes.

Authors:  H Binz; H Wigzell
Journal:  Mol Cell Biochem       Date:  1978-12-22       Impact factor: 3.396

Review 4.  Helper and suppressor T cell factors.

Authors:  R N Germain; B Benacerraf
Journal:  Springer Semin Immunopathol       Date:  1980-05

5.  Activation of T and B lymphocytes in vitro: presence of beta2-microblobulin determinants on allogeneic effect factor.

Authors:  D Armerding; R T Kubo; H M Grey; D H Katz
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205

6.  Genetic control of immune responses in vitro. VI. Experimental conditions for the development of helper T-cell activity specific for the terpolymer L-glutamic aicd60-L-alanine30-L-tyrosine10 (GAT) in nonresponder mice.

Authors:  J A Kapp; C W Pierce; B Benacerraf
Journal:  J Exp Med       Date:  1975-07-01       Impact factor: 14.307

7.  Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.

Authors:  H Waldmann; P Poulton; C Desaymard
Journal:  Immunology       Date:  1976-05       Impact factor: 7.397

8.  Characterization of the dengue virus-induced helper cytokine.

Authors:  P Chaturvedi; R Mukherjee; U C Chaturvedi; A Mathur
Journal:  Int J Exp Pathol       Date:  1992-06       Impact factor: 1.925

9.  Purification of antigen-dependent macrophage migration inhibition factor (MIF) from lymph draining a tuberculin reaction.

Authors:  D M Scott; I McConnell; P Agomo; P J Lachmann
Journal:  Immunology       Date:  1978-04       Impact factor: 7.397

10.  Antigenic properties of T cell antigen-specific receptors isolated from the surface of rabbit and mouse spleen and lymph node cells.

Authors:  J Rejnek; L Tucková; J Zikán; B Ríhová; J Kostka
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099
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