Literature DB >> 4600694

Mutagenesis by mutator gene mutH1 in continuous cultures of Escherichia coli.

E R Nestmann, R F Hill.   

Abstract

Mutability as a function of growth rate was examined in bacterial strains containing mutator gene mutH1. The rate of mutation to bacteriophage T5 resistance was found to be proportional to rate of growth in glucose-limited chemostat cultures. This finding supports the hypothesis that the mutator mutH1 gene product increases the error frequency during deoxyribonucleic acid replication.

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Year:  1974        PMID： 4600694      PMCID： PMC245568          DOI： 10.1128/jb.119.1.33-35.1974

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  20 in total

1.  MUTATION IN CONTINUOUS CULTURES. II. MUTATIONS INDUCED WITH ULTRAVIOLET LIGHT AND 2-AMINOPURINE.

Authors:  H E KUBITSCHEK; H E BENDIGKEIT
Journal:  Mutat Res       Date:  1964-10       Impact factor: 2.433

2.  Acetylornithinase of Escherichia coli: partial purification and some properties.

Authors:  H J VOGEL; D M BONNER
Journal:  J Biol Chem       Date:  1956-01       Impact factor: 5.157

3.  Description of the chemostat.

Authors:  A NOVICK; L SZILARD
Journal:  Science       Date:  1950-12-15       Impact factor: 47.728

4.  Selective mechanisms in bacteria.

Authors:  K C ATWOOD; L K SCHNEIDER; F J RYAN
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1951

5.  Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4.

Authors:  N Muzyczka; R L Poland; M J Bessman
Journal:  J Biol Chem       Date:  1972-11-25       Impact factor: 5.157

6.  Synergistic effect of an Escherichia coli mutator gene on mutagenesis by ultraviolet radiation and by alkylating agents.

Authors:  R F Hill
Journal:  Mutat Res       Date:  1972-01       Impact factor: 2.433

7.  Location of genes controlling excision repair of UV damage and mutator activity in Escherichia coli WP2.

Authors:  R F Hill
Journal:  Mutat Res       Date:  1970-03       Impact factor: 2.433

8.  Isolation, characterization, and genetic analysis of mutator genes in Escherichia coli B and K-12.

Authors:  R M Liberfarb; V Bryson
Journal:  J Bacteriol       Date:  1970-10       Impact factor: 3.490

9.  Do dark repair mechanisms for UV-induced primary damage affect spontaneous mutation?

Authors:  R F Hill
Journal:  Mutat Res       Date:  1968 Nov-Dec       Impact factor: 2.433

10.  Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli.

Authors:  S Wickner; M Wright; J Hurwitz
Journal:  Proc Natl Acad Sci U S A       Date:  1973-05       Impact factor: 11.205
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  2 in total

Review 1.  Recalibrated linkage map of Escherichia coli K-12.

Authors:  B J Bachmann; K B Low; A L Taylor
Journal:  Bacteriol Rev       Date:  1976-03

2.  Antimutagenic effects of spermine and guanosine in continuous cultures of Escherichia coli mutator strain mutH.

Authors:  E R Nestmann
Journal:  Mol Gen Genet       Date:  1977-03-28
  2 in total

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