| Literature DB >> 4599425 |
Abstract
One type of elmbryonic rat brain cell having an epithelioid morphology in the monolayer culture can be transformed by brain extract into cells having extensive processes resembling mature astrocytes. The transforming factor is a protein with a molecular weight of 350,000. A partially purified sample showed that it is active at a concentration as low as 1 x 10(-8)M. The transforming actvity is high in adult brains but low in embryonic brains and tumors of the nervous systems.Entities:
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Year: 1974 PMID： 4599425 DOI： 10.1126/science.185.4145.63
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728