Literature DB >> 1152345

Effects of synthetic somatostatin on endotoxin-induced changes of growth hormone, cortisol and insulin in plasma, blood sugar and blood leukocytes in man.

H Wagner, E Zierden, W H Hauss.   

Abstract

In normal man synthetic somatostatin inhibits the growth hormone response to intravenous administration of endotoxin (Piromen), but exerts no influence on cortisol plasma levels. Endotoxin-induced leukocytosis in blood is significantly reduced by somatostatin. Plasma levels of insulin and the blood sugar in man receiving endotoxin are firstly reduced in a significant manner and then increasing to normal values during somatostatin infusion.

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Year:  1975        PMID: 1152345     DOI: 10.1007/bf01468760

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  22 in total

1.  COMPARISON OF HEMATOLOGIC AND FEBRILE RESPONSE TO ENDOTOXIN IN MAN.

Authors:  S M WOLFF; M RUBENSTEIN; J H MULHOLLAND; D W ALLING
Journal:  Blood       Date:  1965-08       Impact factor: 22.113

2.  Specific inhibition by somatostatin of growth hormone release after hypoglycaemia in normal man.

Authors:  G Copinschi; E Virasoro; L Vanhaelst; R Leclercq; J Golstein; M L'Hermite
Journal:  Clin Endocrinol (Oxf)       Date:  1974-10       Impact factor: 3.478

3.  Effect of somatostatin in patients with acromegaly: suppression of growth hormone, prolactin, insulin and glucose levels.

Authors:  S S Yen; T M Siler; G W DeVane
Journal:  N Engl J Med       Date:  1974-04-25       Impact factor: 91.245

4.  Somatostatin: hypothalamic inhibitor of the endocrine pancreas.

Authors:  D J Koerker; W Ruch; E Chideckel; J Palmer; C J Goodner; J Ensinck; C C Gale
Journal:  Science       Date:  1974-04-26       Impact factor: 47.728

5.  Action of growth-hormone-release inhibitory hormone in healthy men and in acromegaly.

Authors:  R Hall; G M Besser; A V Schally; D H Coy; D Evered; D J Goldie; A J Kastin; A S McNeilly; C H Mortimer; C Phenekos; W M Tunbridge; D Weightman
Journal:  Lancet       Date:  1973-09-15       Impact factor: 79.321

6.  Inhibition of insulin secretion by somatostatin.

Authors:  K G Alberti; N J Christensen; S E Christensen; A P Hansen; J Iversen; K Lundbaek; K Seyer-Hansen; H Orskov
Journal:  Lancet       Date:  1973-12-08       Impact factor: 79.321

7.  Comparison of the effect of the pyrogens, etiocholanolone and bacterial endotoxin on plasma cortisol and growth hormone in man.

Authors:  H R Kimball; M B Lipsett; W D Odell; S M Wolff
Journal:  J Clin Endocrinol Metab       Date:  1968-03       Impact factor: 5.958

8.  Acute suppression of insulin and glucose levels by synthetic somatostatin in normal human subjects.

Authors:  G W DeVane; T M Siler; S S Yen
Journal:  J Clin Endocrinol Metab       Date:  1974-05       Impact factor: 5.958

9.  Radioimmunoassay of human growth hormone using the double antibody technique.

Authors:  F Melani; U Gröschel-Stewart; J Lawecki
Journal:  Acta Endocrinol (Copenh)       Date:  1968-04

10.  Coated charcoal immunoassay of insulin.

Authors:  V Herbert; K S Lau; C W Gottlieb; S J Bleicher
Journal:  J Clin Endocrinol Metab       Date:  1965-10       Impact factor: 5.958

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  2 in total

1.  Leukocyte response to somatostatin in normals and patients with bacterial leukocytosis.

Authors:  E Zierden; K Hengst; H Wagner
Journal:  Klin Wochenschr       Date:  1977-05-15

2.  [Somatostatin -- a review (author's transl)].

Authors:  C Lucke; H J Mitzkat; A von zur Mühlen
Journal:  Klin Wochenschr       Date:  1976-04-01
  2 in total

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