Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The distribution of HLA-Antigens in German patients with idiopathic hemochromatosis.

Literature DB >> 459368

The distribution of HLA-Antigens in German patients with idiopathic hemochromatosis.

Abstract

HLA-phenotypes were determined in 31 (30 unrelated) patients with hemochromatosis and compared to the distribution of HLA-antigens in the general German population. A significant excess of HLA-A3 was observed (76.7% vs. 30.2%). The frequency of HLA-B7 was also increased (53.3% vs. 27.0%). However, the difference did not quite reach the level of statistical significance, when correction for multiple comparisons was made. Our findings are in accord with previous observations for different ethnic groups, indicating an association of IH with the A3/B7 haplotype.

Entities: Disease Species

Mesh：

Substances：
HLA Antigens

Year: 1979 PMID： 459368 DOI： 10.1007/bf01487823

Source DB: PubMed Journal: Klin Wochenschr ISSN： 0023-2173

12 in total

1. Representative HL-A phenotype and haplotype frequencies of the german population.

Authors: E D Albert; S Scholz; J Bertrams; R W Ewald; E Westphal; K W Ratschko; W Spielmann; S Seidl
Journal: Z Immunitatsforsch Exp Klin Immunol Date: 1975-05

2. Letter: HLA antigens in haemochromatosis.

Authors: W G Shewan; S A Mouat; T M Allan
Journal: Br Med J Date: 1976-01-31

3. Letter: HLA antigens in haemochromatosis.

Authors: J M Walters; D W Watt; F M Stevens; C F McCarthy
Journal: Br Med J Date: 1975-11-29

4. Idiopathic hemochromatosis and iron overload in alcoholic liver disease: differentiation by HLA phenotype.

Authors: M Simon; M Bourel; B Genetet; R Fauchet; G Edan; P Brissot
Journal: Gastroenterology Date: 1977-10 Impact factor: 22.682

5. Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.

Authors: M Simon; M Bourel; R Fauchet; B Genetet
Journal: Gut Date: 1976-05 Impact factor: 23.059

6. [HLA-system and internal diseases].

Authors: E Hahn
Journal: Internist (Berl) Date: 1978-08 Impact factor: 0.743

Review 7. The major histocompatibility complex--genetics and biology. (First of three parts).

Authors: F H Bach; J J van Rood
Journal: N Engl J Med Date: 1976-10-07 Impact factor: 91.245

8. Histocompatibility antigens as markers of abnormal iron metabolism in patients with idiopathic haemochromatosis and their relatives.

Authors: A Bomford; A L Eddleston; L A Kennedy; J R Batchelor; R Williams
Journal: Lancet Date: 1977-02-12 Impact factor: 79.321

The distribution of HLA-Antigens in German patients with idiopathic hemochromatosis.

1. Representative HL-A phenotype and haplotype frequencies of the german population.

2. Letter: HLA antigens in haemochromatosis.

3. Letter: HLA antigens in haemochromatosis.

4. Idiopathic hemochromatosis and iron overload in alcoholic liver disease: differentiation by HLA phenotype.

5. Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.

6. [HLA-system and internal diseases].

Review 7. The major histocompatibility complex--genetics and biology. (First of three parts).

8. Histocompatibility antigens as markers of abnormal iron metabolism in patients with idiopathic haemochromatosis and their relatives.

9. HLA-antigens in idiopathic haemochromatosis (i.h.). preliminary report.

10. Association of HLA antigens with idopathic hemochromatosis.

1. HLA as a marker of the hemochromatosis gene in Sweden.

2. Idiopathic familial hemochromatosis: limited disease extent with prolonged survival and arthritis.

3. [Arthropathy in idiopathic hemochromatosis].

4. HLA haplotypes associated with hemochromatosis mutations in the Spanish population.