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Literature DB >> 458873

Evolutionary changes in protein composition -- evidence for an optimal strategy.

Abstract

The information contained in the composition of different proteins of the same family is analyzed. It is found that within each family the gain in information per amino acid replacement is constant. This finding is interpreted to imply that evolutionary changes in proteins follow an "optimal" path in the sense that they maximize the number of potentially functional sequences that can be generated by T accepted point mutations from a given protein, subject to restrictions due to biological function.

Mesh：

Substances：
Proteins

Year: 1979 PMID： 458873 DOI： 10.1007/bf01732754

Source DB: PubMed Journal: J Mol Evol ISSN： 0022-2844 Impact factor: 2.395

52 in total

Evolutionary changes in protein composition -- evidence for an optimal strategy.

1. Entropy of the genetic information and evolution.

2. The amino acid sequence of gnu pancreatic ribonuclease.

3. Amino acid sequence and immunological properties of chalchalaca egg white lysozyme.

4. On the constancy of the evolutionary rate of cistrons.

5. Opossum Hb chain sequence and neutral mutation theory.

6. Conservation of Shannon's redundancy for proteins.

7. Amino acid composition of proteins as a product of molecular evolution.

8. Amino acid sequence of Spirulina platensis ferredoxin: a far divergency of blue-green algal ferredoxins.

9. The amino acid sequence of ferredoxin II from Chlorobium limicola, a photosynthetic green bacterium.

10. The amino acid sequence of cytochrome c from Solanum tuberosum (potato).

1. Neutral adaptation of the genetic code to double-strand coding.