Literature DB >> 458036

Antipyrine elimination in critically ill patients.

L Mirvis, N Buchanan, C Eyberg.   

Abstract

Antipyrine kinetics were studied in 12 critically ill patients. Antipyrine half life was found to be short (6.5 +/- 3.4 h), this did not alter over 4 days of acute illness, although there was a tendency for antipyrine clearance to decrease over that time period. The need for further pharmacological studies in critically ill patients is stressed.

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Year:  1979        PMID： 458036     DOI： 10.1007/bf01686049

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN： 0342-4642            Impact factor:   17.440


  9 in total

1.  The use of antipyrine in the measurement of total body water in man.

Authors:  R SOBERMAN; B B BRODIE
Journal:  J Biol Chem       Date:  1949-05       Impact factor: 5.157

2.  The metabolism of phenobarbitone, phenytoin and antipyrine in Black patients.

Authors:  N Buchanan; P Bill; G Moodley; C Eyberg
Journal:  S Afr Med J       Date:  1977-08-27

3.  Environmental effects on antipyrine half-life in man.

Authors:  H S Fraser; J C Mucklow; C J Bulpitt; C Khan; G Mould; C T Dollery
Journal:  Clin Pharmacol Ther       Date:  1977-11       Impact factor: 6.875

4.  Immediate decrease by hydrocortisone of the plasma half-life of antipyrine.

Authors:  A Breckenridge; C W Burke; D S Davies; M L Orme
Journal:  Br J Pharmacol       Date:  1973-02       Impact factor: 8.739

5.  Mechanism of hepatic drug oxidation and its relationship to individual differences in rates of oxidation in man.

Authors:  D S Davies; S S Thorgeirsson
Journal:  Ann N Y Acad Sci       Date:  1971-07-06       Impact factor: 5.691

6.  The effect of arterial oxygen tension on antipyrine half-time in plasma.

Authors:  J F Cumming
Journal:  Clin Pharmacol Ther       Date:  1976-04       Impact factor: 6.875

7.  Determinants of serum antipyrine half-lives in patients with liver disease.

Authors:  R A Branch; C M Herbert; A E Read
Journal:  Gut       Date:  1973-07       Impact factor: 23.059

8.  Drug utilization in a general intensive care unit.

Authors:  N Buchanan; R D Cane
Journal:  Intensive Care Med       Date:  1978-04       Impact factor: 17.440

9.  Altered elimination of antipyrine in patients with acute viral hepatitis.

Authors:  D A Burnett; A J Barak; D J Tuma; M F Sorrell
Journal:  Gut       Date:  1976-05       Impact factor: 23.059
  9 in total
  1 in total

Review 1.  Pharmacokinetics and pharmacodynamics of sedatives and analgesics in the treatment of agitated critically ill patients.

Authors:  B K Wagner; D A O'Hara
Journal:  Clin Pharmacokinet       Date:  1997-12       Impact factor: 6.447
  1 in total

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