Literature DB >> 4564407

Ribosomal vaccines. I. Immunogenicity of ribosomal fractions isolated from Salmonella typhimurium and Yersinia pestis.

W Johnson.   

Abstract

The immunogenicity of ribosomes and ribosomal subfractions isolated from Yersina pestis and Salmonella typhimurium has been studied. Ribosomes and ribosomal protein isolated from S. typhimurium protected mice against lethal challenge. Ribosomal ribonucleic acid isolated by phenol extraction failed to induce any significant level of protection in mice. None of the ribosomes or ribosomal subfractions isolated from Y. pestis were effective in inducing immunity to lethal challenge. These results suggest that the immunogen of the ribosomal vaccine is protein.

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Year:  1972        PMID： 4564407      PMCID： PMC422469          DOI： 10.1128/iai.5.6.947-952.1972

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  Pesticins. II. Production of pesticin I and II.

Authors:  R R BRUBAKER; M J SURGALLA
Journal:  J Bacteriol       Date:  1962-09       Impact factor: 3.490

2.  Experimental salmonellosis: differential passive transfer of immunity with serum and cells obtained from ribosomal and ribonucleic acid-immunized mice.

Authors:  M R Venneman; L J Berry
Journal:  J Reticuloendothel Soc       Date:  1971-05

3.  Extraction and isolation of individual ribosomal proteins from Escherichia coli.

Authors:  S Fogel; P S Sypherd
Journal:  J Bacteriol       Date:  1968-08       Impact factor: 3.490

4.  Antibacterial immunity induced by ribosomal vaccines.

Authors:  S H Winston; L J Berry
Journal:  J Reticuloendothel Soc       Date:  1970-07

5.  Isolation and partial characterization of an immunogenic moiety obtained from Salmonella typhimurium.

Authors:  M R Venneman; N J Bigley
Journal:  J Bacteriol       Date:  1969-10       Impact factor: 3.490

6.  Effect of trypsin and ribonuclease on the immunogenic activity of ribosomes and ribonucleic acid isolated from Mycobacterium tuberculosis.

Authors:  A S Youmans; G P Youmans
Journal:  J Bacteriol       Date:  1966-06       Impact factor: 3.490

7.  Protection against pneumococcal infection by a ribosomal preparation.

Authors:  H C Thompson; I S Snyder
Journal:  Infect Immun       Date:  1971-01       Impact factor: 3.441

8.  Failure of synthetic polynucleotides to affect the immunogenicity of mycobacterial ribonucleic Acid and ribosomal protein preparations.

Authors:  A S Youmans; G P Youmans
Journal:  Infect Immun       Date:  1971-01       Impact factor: 3.441

9.  Demonstration in tissue culture of lymphocyte-mediated immunity to tuberculosis.

Authors:  R J Patterson; G P Youmans
Journal:  Infect Immun       Date:  1970-06       Impact factor: 3.441

10.  Mechanisms of acquired resistance in mouse typhoid.

Authors:  R V Blanden; G B Mackaness; F M Collins
Journal:  J Exp Med       Date:  1966-10-01       Impact factor: 14.307
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  32 in total

1.  Evidence for an extrinsic immunogen in effective ribosomal vaccines from Salmonella typhimurium.

Authors:  P Hoops; N E Prather; J Berry; J M Ravel
Journal:  Infect Immun       Date:  1976-04       Impact factor: 3.441

2.  Immuno-stimulation by a ribosomal vaccine associated with a bacterial cell wall adjuvant in humans.

Authors:  F B Michel; L Dussourd D'Hinterland; J Bousquet; A M Pinel; G Normier
Journal:  Infect Immun       Date:  1978-06       Impact factor: 3.441

3.  Role of endotoxin contamination in ribiosomal vaccines prepared from Salmonella typhimurium.

Authors:  M L Misfeldt; W Johnson
Journal:  Infect Immun       Date:  1977-07       Impact factor: 3.441

4.  Ribosomal vaccines. II. Specificity of the immune response to ribosomal ribonucleic acid and protein isolated from Salmonella typhimurium.

Authors:  W Johnson
Journal:  Infect Immun       Date:  1973-09       Impact factor: 3.441

5.  Delayed dermal hypersensitivity in rhesus monkeys (Macaca mulatta) immunized against Plasmodium knowlesi.

Authors:  E J Cabrera; C A Speer; R H Schenkel; M L Barr; P H Silverman
Journal:  Z Parasitenkd       Date:  1976-07-27

6.  The immunogenic activity of ribosomal fractions derived from Brucella abortus.

Authors:  M J Corbel
Journal:  J Hyg (Lond)       Date:  1976-02

7.  Immunogenicity of ribosomal vaccines isolated from group A, type 14 Streptococcus pyogenes.

Authors:  W O Schalla; W Johnson
Journal:  Infect Immun       Date:  1975-06       Impact factor: 3.441

8.  Capsular serotypic specificity of the protection conferred on mice by Klebsiella pneumoniae ribosomal preparations.

Authors:  M Riottot; J M Fournier; J Pillot
Journal:  Infect Immun       Date:  1979-05       Impact factor: 3.441

9.  Artificial Salmonella vaccines: Salmonella typhimurium O-antigen-specific oligosaccharide-protein conjugates elicit protective antibodies in rabbits and mice.

Authors:  S B Svenson; A A Lindberg
Journal:  Infect Immun       Date:  1981-05       Impact factor: 3.441

10.  Variability of protection in inbred mice induced by a ribosomal vaccine prepared from Salmonella typhimurium.

Authors:  M L Misfeldt; W Johnson
Journal:  Infect Immun       Date:  1976-09       Impact factor: 3.441
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