Literature DB >> 4553844

Isoleucine accumulation by regulatory mutants of Serratia marcescens: lack of both feedback inhibition and repression.

M Kisumi, S Komatsubara, M Sugiura, I Chibata.   

Abstract

Double mutants of Serratia marcescens resistant to isoleucine hydroxamate and alpha-aminobutyric acid accumulated large amounts of isoleucine in a salts-sugar medium and lacked both feedback inhibition and repression of the isoleucine biosynthesis.

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Year:  1972        PMID： 4553844      PMCID： PMC247477          DOI： 10.1128/jb.110.2.761-763.1972

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  9 in total

1.  Studies on the isoleucine fermentation. I. Screening of organisms and investigation of cultural conditions.

Authors:  M KISUMI
Journal:  J Biochem       Date:  1962-12       Impact factor: 3.387

2.  Specific binding of leucyl transfer RNA to an immature form of L-threonine deaminase: its implications in repression.

Authors:  G W Hatfield; R O Burns
Journal:  Proc Natl Acad Sci U S A       Date:  1970-08       Impact factor: 11.205

3.  [The biosynthesis of isoleucine and valine in Hydrogenomonas H 16].

Authors:  M Reh; H G Schlegel
Journal:  Arch Mikrobiol       Date:  1969

4.  Properties of isoleucine hydroxamate-resistant mutants of Serratia marcescens.

Authors:  M Kisumi; S Komatsubara; M Sugiura; I Chibata
Journal:  J Gen Microbiol       Date:  1971-12

5.  Multivalent repression and genetic depression of isoleucine-valine biosynthetic enzymes in Serratia marcescens.

Authors:  M Kisumi; S Komatsubara; I Chibata
Journal:  J Bacteriol       Date:  1971-09       Impact factor: 3.490

6.  Isoleucine hydroxamate, an isoleucine antagonist.

Authors:  M Kisumi; S Komatsubara; M Sugiura; I Chibata
Journal:  J Bacteriol       Date:  1971-09       Impact factor: 3.490

7.  Isoleucine and valine metabolism in Escherichia coli. V. Antagonism between isoleucine and valine.

Authors:  H E UMBARGER; B BROWN
Journal:  J Bacteriol       Date:  1955-08       Impact factor: 3.490

8.  REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. I. GENETIC DEREPRESSION OF ENZYME FORMATION.

Authors:  T RAMAKRISHNAN; E A ADELBERG
Journal:  J Bacteriol       Date:  1964-03       Impact factor: 3.490

9.  Valine accumulation by alpha-aminobutyric acid-resistant mutants of Serratia marcescens.

Authors:  M Kisumi; S Komatsubara; I Chibata
Journal:  J Bacteriol       Date:  1971-05       Impact factor: 3.490
  9 in total
  6 in total

1.  Threonine production by regulatory mutants of Serratia marcescens.

Authors:  S Komatsubara; M Kisumi; K Murata; I Chibata
Journal:  Appl Environ Microbiol       Date:  1978-05       Impact factor: 4.792

2.  Threonine degradation by Serratia marcescens.

Authors:  S Komatsubara; K Murata; M Kisumi; I Chibata
Journal:  J Bacteriol       Date:  1978-08       Impact factor: 3.490

3.  l-Isoleucine Production with Corynebacterium glutamicum: Further Flux Increase and Limitation of Export.

Authors:  S Morbach; H Sahm; L Eggeling
Journal:  Appl Environ Microbiol       Date:  1996-12       Impact factor: 4.792

4.  L-Histidine production by histidase-less regulatory mutants of Serratia marcescens constructed by transduction.

Authors:  M Kisumi; N Nakanishi; T Takagi; I Chibata
Journal:  Appl Environ Microbiol       Date:  1977-11       Impact factor: 4.792

5.  Enhancement of isoleucine hydroxamate-mediated growth inhibition and improvement of isoleucine-producing strains of Serratia marcescens.

Authors:  M Kisumi; S Komatsubara; I Chibata
Journal:  Appl Environ Microbiol       Date:  1977-12       Impact factor: 4.792

6.  Transductional construction of a threonine-producing strain of Serratia marcescens.

Authors:  S Komatsubara; M Kisumi; I Chibata
Journal:  Appl Environ Microbiol       Date:  1979-12       Impact factor: 4.792
  6 in total

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