| Literature DB >> 4553001 |
F S Southwick, H S Carr, G A Carden, R M D'Alisa, H S Rosenkranz.
Abstract
Exposure of Escherichia coli to critical acridine orange (AO) concentrations did not result in loss of viability. However, the deoxyribonucleic acid (DNA) of cells exposed to such agents was rapidly degraded and repolymerized. On the other hand, a bacterium deficient in DNA repair (pol A(1) (-), lacking DNA polymerase) was sensitive to the action of AO. The DNA of such cells was also degraded but it was not repaired.Entities:
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Year: 1972 PMID: 4553001 PMCID: PMC247425 DOI: 10.1128/jb.110.1.439-441.1972
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490