Literature DB >> 453824

Metabolism of (+/-)-N-(n-propyl) amphetamine by Cunninghamella echinulata.

R T Coutts, B C Foster, G R Jones, G E Myers.   

Abstract

(+/-)-N-(n-propyl) amphetamine (I), a secondary amine, was readily metabolized by Cumminghamella echinulata. The products included known C- and N-oxygenated mammalian metabolites as well as N-acetylamphetamine and were identified by gas chromatography and mass spectrometry.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 453824      PMCID： PMC243233          DOI： 10.1128/aem.37.3.429-432.1979

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  15 in total

1.  Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: evidence for the presence of cytochrome P-450.

Authors:  J P Ferris; L H MacDonald; M A Patrie; M A Martin
Journal:  Arch Biochem Biophys       Date:  1976-08       Impact factor: 4.013

2.  Metabolism in vitro of N-methylamphetamine with rat liver homogenates.

Authors:  R T Coutts; S H Kovach
Journal:  Biochem Pharmacol       Date:  1977-06-01       Impact factor: 5.858

3.  Oxidation of aliphatic hydroxylamines in aqueous solutions.

Authors:  A H Beckett; A R Purkaystha; P H Morgan
Journal:  J Pharm Pharmacol       Date:  1977-01       Impact factor: 3.765

4.  Urinary excretion of phenolic metabolites of N-(n-propyl)amphetamine in man.

Authors:  R T Coutts; G W Dawson
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1977-06

5.  Monooxygenase activity in Cunninghamella bainieri: evidence for a fungal system similar to liver microsomes.

Authors:  J P Ferris; M J Fasco; F L Stylianopoulou; D M Jerina; J W Daly; A M Jeffrey
Journal:  Arch Biochem Biophys       Date:  1973-05       Impact factor: 4.013

6.  Microbial models of mammalian metabolism. Aromatic hydroxylation.

Authors:  R V Smith; J P Rosazza
Journal:  Arch Biochem Biophys       Date:  1974-04-02       Impact factor: 4.013

7.  Metabolism of amphetamines. Identification of N-oxygenated products by gas chromatography and mass spectrometry.

Authors:  A H Beckett; R T Coutts; F A Ogunbona
Journal:  J Pharm Pharmacol       Date:  1973-09       Impact factor: 3.765

8.  The demethylation of methamphetamine by intestinal microflora.

Authors:  J Caldwell; G M Hawksworth
Journal:  J Pharm Pharmacol       Date:  1973-05       Impact factor: 3.765

9.  In vitro metabolism of 1-phenyl-2-(n-propylamino) propane (N-propylamphetamine) by rat liver homogenates.

Authors:  R T Coutts; G W Dawson; A H Beckett
Journal:  J Pharm Pharmacol       Date:  1976-11       Impact factor: 3.765

10.  Tryptophol formation by Zygosaccharomyces priorianus.

Authors:  J P Rosazza; R Juhl; P Davis
Journal:  Appl Microbiol       Date:  1973-07
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.