Literature DB >> 11289

In vitro metabolism of 1-phenyl-2-(n-propylamino) propane (N-propylamphetamine) by rat liver homogenates.

R T Coutts, G W Dawson, A H Beckett.   

Abstract

In vitro incubation of (+/-)-N-(n-propyl)amphetamine (NPA) with the 12000 g supernatant fraction of rat liver hmogenate resulted in the formation of two N-oxygenated products identified as N-hydroxy-1-phenyl-2(n-propylamino)propane and N-[(1-methyl-2-phenyl) ethyl]-1-propanamine N-oxide by g.l.c., g.l.c.-m.s. and t.l.c. Amphetamine, phenylacetone,...

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Year:  1976        PMID: 11289     DOI: 10.1111/j.2042-7158.1976.tb04063.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  1 in total

1.  Metabolism of (+/-)-N-(n-propyl) amphetamine by Cunninghamella echinulata.

Authors:  R T Coutts; B C Foster; G R Jones; G E Myers
Journal:  Appl Environ Microbiol       Date:  1979-03       Impact factor: 4.792

  1 in total

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