Literature DB >> 4530990

Significance of plasma dopamine beta-hydroxylase activity as an index of sympathetic neuronal function.

J L Reid, I J Kopin.   

Abstract

Plasma norepinephrine and dopamine beta-hydroxylase (EC 1.14.17.1) activity were measured in rats. Adrenergic neuron blockade with bretylium for 4 hr and ganglion blockade with chlorisondamine for 72 hr lowered plasma norepinephrine. Neither treatment altered plasma dopamine beta-hydroxylase activity. Phenoxybenzamine for up to 48 hr markedly raised plasma norepinephrine and transiently lowered plasma dopamine beta-hydroxylase at 24 hr. Prolonged pharmacological modification of sympathetic nervous activity and plasma norepinephrine were not attended by parallel changes in circulating dopamine beta-hydroxylase activity. Plasma dopamine beta-hydroxylase activity does not appear to be a sensitive index of prolonged alterations in sympathetic neural activity. Norepinephrine in plasma, however, appears to reflect sensitively and accurately the rate of release of the neurotransmitter.

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Year:  1974        PMID： 4530990      PMCID： PMC433890          DOI： 10.1073/pnas.71.11.4392

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

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Authors:  A Dahlström
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1971-06-17       Impact factor: 6.237

5.  Serum dopamine-beta-hydroxylase activity.

Authors:  R Weinshilboum; J Axelrod
Journal:  Circ Res       Date:  1971-03       Impact factor: 17.367

6.  Induction of dopamine- -hydroxylase and tyrosine hydroxylase in rat hearts and sympathetic ganglia.

Authors:  P B Molinoff; S Brimijoin; J Axelrod
Journal:  J Pharmacol Exp Ther       Date:  1972-07       Impact factor: 4.030

7.  Proportional release of norepinephrine and dopamine- -hydroxylase from sympathetic nerves.

Authors:  R M Weinshilboum; N B Thoa; D G Johnson; I J Kopin; J Axelrod
Journal:  Science       Date:  1971-12-24       Impact factor: 47.728

8.  Plasma dopamine beta-hydroxylase: a possible aid in the study and evaluation of hypertension.

Authors:  S M Schanberg; R A Stone; N Kirshner; J C Gunnells; R R Robinson
Journal:  Science       Date:  1974-02-08       Impact factor: 47.728

9.  Serum dopamine- -hydroxylase: decrease after chemical sympathectomy.

Authors:  R Weinshilboum; J Axelrod
Journal:  Science       Date:  1971-09-03       Impact factor: 47.728

10.  Inhibition of release of dopamine- -hydroxylase and norepinephrine from sympathetic nerves by colchicine, vinblastine, or cytochalasin-B (hypogastric nerve stimulation-exocytosis-microtubules-microfilaments-guinea pig).

Authors:  N B Thoa; G F Wooten; J Axelrod; I J Kopin
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205
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  9 in total

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Authors:  T K Keeton; A M Biediger
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2.  Dopamine-beta-hydroxylase. An index of adrenergic function in hypertensive patients.

Authors:  R A Stone
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3.  Hypothalamic dopamine-beta-hydroxylase activity: fluctuations with time of day and their modifications by intracranial surgery, adrenalectomy, and pinealectomy.

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4.  Tissue and plasma catecholamines and dopamine beta-hydroxylase activity of various animal species after neurogenic sympathetic stimulation.

Authors:  J M Arnaiz; A G García; J F Horga; S M Kirpekar
Journal:  J Physiol       Date:  1978-12       Impact factor: 5.182

5.  Serum dopamine-beta-hydroxylase activity: clinical applications in child psychiatry.

Authors:  J G Young; R M Kyprie; N T Ross; D J Cohen
Journal:  J Autism Dev Disord       Date:  1980-03

6.  Changes in plasma dopamine beta-hydroxylase activity induced by stimulation of the complete sympathetic outflow in the pithed rat.

Authors:  A G García; F Pelayo; P Sánchez-García
Journal:  J Physiol       Date:  1978-05       Impact factor: 5.182

7.  Dopamine-β-Hydroxylase Activity and Levels of Its Cofactors and Other Biochemical Parameters in the Serum of Arsenicosis Patients of Bangladesh.

Authors:  M Khalilur Rahman; M Iqbal Choudhary; M Arif; M Monzur Morshed
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8.  Dopamine-β-Hydroxylase (DBH), Its Cofactors and Other Biochemical Parameters in the Serum of Neurological Patients in Bangladesh.

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9.  Developmental Changes of Catecholamine-mediating Enzyme - Dopamine-β- Hydroxylase and Its Cofactors in Central and Peripheral Tissues and Serum of Long-Evans Rats.

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  9 in total

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