Literature DB >> 4507608

A unifying hypothesis concerning the nature of malignant growth.

R W Holley.   

Abstract

It is suggested that the crucial change in a malignant cell is an alteration in the cell surface membrane that results in increased internal concentrations of nutrients that regulate cell growth.

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Year:  1972        PMID: 4507608      PMCID: PMC389657          DOI: 10.1073/pnas.69.10.2840

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  18 in total

1.  Temperature-dependent alterations in sugar transport in cells infected by a temperature-sensitive mutant of Rous sarcoma virus.

Authors:  G S Martin; S Venuta; M Weber; H Rubin
Journal:  Proc Natl Acad Sci U S A       Date:  1971-11       Impact factor: 11.205

2.  Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport.

Authors:  M Hatanaka; H Hanafusa
Journal:  Virology       Date:  1970-08       Impact factor: 3.616

3.  Evidence for a functional change in the plasma membrane of murine sarcoma virus-infected mouse embryo cells. Transport and transport-associated phosphorylation of 14C-2-deoxy-D-glucose.

Authors:  M Hatanaka; C Augl; R V Gilden
Journal:  J Biol Chem       Date:  1970-02-25       Impact factor: 5.157

4.  Carcinogenesis by avian sarcoma viruses. X. The decreased requirement for insulin-replaceable activity in serum for cell multiplication.

Authors:  H M Temin
Journal:  Int J Cancer       Date:  1968-11-15       Impact factor: 7.396

5.  Transport of amino acids by confluent and nonconfluent 3T3 and polyoma virus-transformed 3T3 cells growing on glass cover slips.

Authors:  D O Foster; A B Pardee
Journal:  J Biol Chem       Date:  1969-05-25       Impact factor: 5.157

6.  Migration of mouse 3T3 fibroblasts in response to a serum factor.

Authors:  A Lipton; I Klinger; D Paul; R W Holley
Journal:  Proc Natl Acad Sci U S A       Date:  1971-11       Impact factor: 11.205

7.  "Pleiotypic response".

Authors:  A Hershko; P Mamont; R Shields; G M Tomkins
Journal:  Nat New Biol       Date:  1971-08

8.  Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts.

Authors:  D Paul; A Lipton; I Klinger
Journal:  Proc Natl Acad Sci U S A       Date:  1971-03       Impact factor: 11.205

9.  Transport changes rapidly initiated by serum addition to "contact inhibited" 3T3 cells.

Authors:  D D Cunningham; A B Pardee
Journal:  Proc Natl Acad Sci U S A       Date:  1969-11       Impact factor: 11.205

10.  Alterations in the characteristics of sugar uptake by mouse cells transformed by murine sarcoma viruses.

Authors:  M Hatanaka; R J Huebner; R V Gilden
Journal:  J Natl Cancer Inst       Date:  1969-11       Impact factor: 13.506

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  49 in total

1.  Sodium-stimulated amino acid uptake into isolated membrane vesicles from Balb/c 3T3 cells transformed by simian virus 40.

Authors:  D C Quinlan; J R Parnes; R Shalom; T Q Garvey; K J Isselbacher; J Hochstadt
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

2.  Activity of glycosidases (beta-N-acetyloglucosaminidase, alpha-mannosidase, and beta-galactosidase) in the uterine luminal fluid of cows after multiple ovulation.

Authors:  Theodora Tsiligianni; Georgios S Amiridis; Emmanuel Vainas
Journal:  Can J Vet Res       Date:  2007-10       Impact factor: 1.310

3.  Surface morphology of normal and neoplastic rat cells.

Authors:  M W Cloyd; D D Bigner
Journal:  Am J Pathol       Date:  1977-07       Impact factor: 4.307

4.  Fibroblasts isolated from human pterygia exhibit transformed cell characteristics.

Authors:  J K Chen; R J Tsai; S S Lin
Journal:  In Vitro Cell Dev Biol Anim       Date:  1994-04       Impact factor: 2.416

5.  A unifying model of the cell proliferation emphasizing plasma membrane fluxes.

Authors:  E Cervén
Journal:  Experientia       Date:  1990-10-15

6.  Metabolic iteration, evolution and cognition in cellular proliferation.

Authors:  E Cervén
Journal:  Experientia       Date:  1987-10-15

7.  Phospholipid metabolism in the initiation of renal compensatory growth after acute reduction of renal mass.

Authors:  F G Toback; P D Smith; L M Lowenstein
Journal:  J Clin Invest       Date:  1974-07       Impact factor: 14.808

8.  Effect of imposed serum deprivation on growth of the mouse 3T3 cell. Dissociation from changes in potassium ion transport as measured from [86Rb)rubidium ion uptake.

Authors:  J T Tupper; L Zografos
Journal:  Biochem J       Date:  1978-09-15       Impact factor: 3.857

9.  Growth limitation of BHK-21 cells and its relation to folate metabolism.

Authors:  A I Neugut; I B Weinstein
Journal:  In Vitro       Date:  1979-05

10.  Choline pathways during normal and stimulated renal growth in rats.

Authors:  G H Bean; L M Lowenstein
Journal:  J Clin Invest       Date:  1978-06       Impact factor: 14.808

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