Literature DB >> 4504342

Amphetamines: correlation of activity with stability of molecular complexes.

M T Sung, J A Parker.   

Abstract

Molecular complexes have been prepared from several biologically active methoxyamphetamines and 1,4-dinitrobenzene. The association constants of these complexes, determined by nuclear magnetic resonance measurements, correlate linearly with the threshold hallucinogenic dose in humans.

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Year:  1972        PMID: 4504342      PMCID: PMC426698          DOI: 10.1073/pnas.69.6.1346

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  9 in total

1.  Correlation between activity and electronic state of hallucinogenic amphetamines.

Authors:  S Kang; J P Green
Journal:  Nature       Date:  1970-05-16       Impact factor: 49.962

2.  Native fluorescence and hallucinogenic potency of some amphetamines.

Authors:  F Antun; J R Smythies; F Benington; R D Morin; C F Barfknecht; D E Nichols
Journal:  Experientia       Date:  1971-01-15

3.  Receptors: localization and specificity of binding of serotonin in the central nervous system.

Authors:  S G Alivisatos; F Ungar; P K Seth; L P Levitt; A J Geroulis; T S Meyer
Journal:  Science       Date:  1971-02-26       Impact factor: 47.728

4.  Structure--activity relationships of one-ring psychotomimetics.

Authors:  A T Shulgin; T Sargent; C Naranjo
Journal:  Nature       Date:  1969-02-08       Impact factor: 49.962

5.  Psychedelic drugs: steric factors that predict psychotropic activity.

Authors:  S H Snyder; E Richelson
Journal:  Proc Natl Acad Sci U S A       Date:  1968-05       Impact factor: 11.205

6.  A relationship between the hallucinogenic activity of drugs and their electronic configuration.

Authors:  S H Snyder; C R Merril
Journal:  Proc Natl Acad Sci U S A       Date:  1965-07       Impact factor: 11.205

7.  Electron-donor-acceptor complex formation by compounds of biological interest. II. The association constants of various I,4-dinitrobenzene-phenothiazine drug complexes.

Authors:  R Foster; C A Fyfe
Journal:  Bibl Laeger       Date:  1966-03-14

8.  On the mechanism of action of chlorpromazine.

Authors:  G KARREMAN; I ISENBERG; A SZENT-GYORGYI
Journal:  Science       Date:  1959-10-30       Impact factor: 47.728

9.  Nutmeg as a narcotic. A contribution to the chemistry and pharmacology of nutmeg (Myristica fragrans).

Authors:  D A Kalbhen
Journal:  Angew Chem Int Ed Engl       Date:  1971-06       Impact factor: 15.336

  9 in total

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