Literature DB >> 4479776

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 2: in vivo parenteral pharmacology and acute toxicity in mice. Comparison with morphine, codeine and diphenoxylate.

C J Niemegeers, F M Lenaerts, P A Janssen.   

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Year:  1974        PMID: 4479776

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


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  14 in total

1.  Loperamide and ileostomy output--placebo-controled double-blind crossover study.

Authors:  G N Tytgat; K Huibregtse
Journal:  Br Med J       Date:  1975-06-21

2.  Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol.

Authors:  Stefan Schunk; Klaus Linz; Claudia Hinze; Sven Frormann; Stefan Oberbörsch; Bernd Sundermann; Saskia Zemolka; Werner Englberger; Tieno Germann; Thomas Christoph; Babette-Y Kögel; Wolfgang Schröder; Stephanie Harlfinger; Derek Saunders; Achim Kless; Hans Schick; Helmut Sonnenschein
Journal:  ACS Med Chem Lett       Date:  2014-06-24       Impact factor: 4.345

3.  Effect of loperamide on fecal output and composition in well-established ileostomy and ileorectal anastomosis.

Authors:  G N Tytgat; K Huibregtse; J Dagevos; A van den Ende
Journal:  Am J Dig Dis       Date:  1977-08

4.  Inhibition of stimulated fluid secretion in the rat small and large intestine by opiate agonists.

Authors:  E Beubler; F Lembeck
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-03       Impact factor: 3.000

5.  Stimulation of gastrointestinal motility by loperamide in dogs.

Authors:  J Fioramonti; M J Fargeas; L Bueno
Journal:  Dig Dis Sci       Date:  1987-06       Impact factor: 3.199

6.  Effect of codeine and loperamide on upper intestinal transit and absorption in normal subjects and patients with postvagotomy diarrhoea.

Authors:  J D O'Brien; D G Thompson; A McIntyre; W R Burnham; E Walker
Journal:  Gut       Date:  1988-03       Impact factor: 23.059

7.  Double-blind placebo-controlled study of loperamide (Imodium) in chronic diarrhoea caused by ileocolic disease or resection.

Authors:  P Mainguet; R Fiasse
Journal:  Gut       Date:  1977-07       Impact factor: 23.059

8.  P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Authors:  A H Schinkel; E Wagenaar; C A Mol; L van Deemter
Journal:  J Clin Invest       Date:  1996-06-01       Impact factor: 14.808

Review 9.  Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea.

Authors:  R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-01       Impact factor: 9.546

10.  Inhibitory effect of opiates on male rat sexual behavior may be mediated by opiate receptors outside the central nervous system.

Authors:  A Agmo; J Rojas; P Vázquez
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

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